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Table 2 Non-pharmacological interventions investigated in randomized clinical trials for preventing clotting during continuous renal replacement therapy.

From: How to Prolong Filter Life During Continuous Renal Replacement Therapy?

Interventions

Number of trials

Number of participants in the trials

Modes

CVVH, CVVHD, or CVVHDF

10

520

Pre-dilution or post-dilution

2

48

Blood flow

Higher blood flow or standard blood flow

2

134

Catheter types

Long or short catheter

1

100

Surface-modified double-lumen catheter

1

236

Filter types

AN69ST

3

76

More and shorter hollow fiber

1

6

Flat plate fibera

1

38

Filter with a larger membrane surface areaa

1

38

Others

Single- or double-site infusion anticoagulationa

1

38

  1. aFrom one study embedding three comparisons. CVVH continuous venovenous hemofiltration, CVVHD continuous venovenous hemodialysis, CVVHDF continuous venovenous hemodiafiltration, AN69ST polyethylenimine-treated AN69 membrane