|
Parameter
|
Total Case Control Cohort (n = 215)
|
|---|
|
Control (n = 168)
|
Cases (n = 47)
|
p value
|
|---|
|
LOS Hospital (days)
|
24 (IQR 12–48)
|
33 (IQR 19–53)
|
0.033
|
|
LOS Intensive Care (days)
|
20 (IQR 7–42)
|
24 (IQR 17–43)
|
0.020
|
|
SAPS maximum
|
53 (IQR 40–65)
|
64 (IQR 50–69)
|
0.001
|
|
IL-6 maximum (ng/l)
|
461.4 (IQR 133–1634)
|
1005 (IQR 203–4789)
|
0.008
|
|
PCT maximum (µg/l)
|
3.23 (IQR 0.64–13.7)
|
7.48 (IQR 3.95–16.27)
|
0.012
|
|
ECMO
|
20.8% (n = 35)
|
21.3% (n = 10)
|
0.947
|
|
ARDS
|
None
|
18.45% (n = 31)
|
n = 0
|
0.007
|
|
Mild
|
1.8% (n = 3)
|
2.1% (n = 1)
|
|
Moderate
|
19.6% (n = 33)
|
14.9% (n = 7)
|
|
Severe
|
60.1% (n = 101)
|
83.0% (n = 39)
|
|
In-hospital death
|
47.6% (n = 80)
|
63.8% (n = 30)
|
0.049
|
|
Renal replacement therapy
|
41.1% (n = 69)
|
59.6% (n = 28)
|
0.024
|
- P-value ≤ 0.05 was defined as statistically significant and presented as bold
- LOS, length of stay; PCT, procalcitonin; SAPS, simplified acute physiology score; IL-6, interleukin-6; ECMO, extra-corporeal membrane oxygenation; ARDS, acute respiratory distress syndrome; IQR, inter quartile range
