Table 2 Univariate comparison of endpoint parameters in CAPA cases and controls
Parameter | Total Case Control Cohort (n = 215) | |||
|---|---|---|---|---|
Control (n = 168) | Cases (n = 47) | p value | ||
LOS Hospital (days) | 24 (IQR 12–48) | 33 (IQR 19–53) | 0.033 | |
LOS Intensive Care (days) | 20 (IQR 7–42) | 24 (IQR 17–43) | 0.020 | |
SAPS maximum | 53 (IQR 40–65) | 64 (IQR 50–69) | 0.001 | |
IL-6 maximum (ng/l) | 461.4 (IQR 133–1634) | 1005 (IQR 203–4789) | 0.008 | |
PCT maximum (µg/l) | 3.23 (IQR 0.64–13.7) | 7.48 (IQR 3.95–16.27) | 0.012 | |
ECMO | 20.8% (n = 35) | 21.3% (n = 10) | 0.947 | |
ARDS | None | 18.45% (n = 31) | n = 0 | 0.007 |
Mild | 1.8% (n = 3) | 2.1% (n = 1) | ||
Moderate | 19.6% (n = 33) | 14.9% (n = 7) | ||
Severe | 60.1% (n = 101) | 83.0% (n = 39) | ||
In-hospital death | 47.6% (n = 80) | 63.8% (n = 30) | 0.049 | |
Renal replacement therapy | 41.1% (n = 69) | 59.6% (n = 28) | 0.024 | |