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Table 2 Univariate comparison of endpoint parameters in CAPA cases and controls

From: Corticosteroids as risk factor for COVID-19-associated pulmonary aspergillosis in intensive care patients

Parameter Total Case Control Cohort (n = 215)
Control (n = 168) Cases (n = 47) p value
LOS Hospital (days) 24 (IQR 12–48) 33 (IQR 19–53) 0.033
LOS Intensive Care (days) 20 (IQR 7–42) 24 (IQR 17–43) 0.020
SAPS maximum 53 (IQR 40–65) 64 (IQR 50–69) 0.001
IL-6 maximum (ng/l) 461.4 (IQR 133–1634) 1005 (IQR 203–4789) 0.008
PCT maximum (µg/l) 3.23 (IQR 0.64–13.7) 7.48 (IQR 3.95–16.27) 0.012
ECMO 20.8% (n = 35) 21.3% (n = 10) 0.947
ARDS None 18.45% (n = 31) n = 0 0.007
Mild 1.8% (n = 3) 2.1% (n = 1)
Moderate 19.6% (n = 33) 14.9% (n = 7)
Severe 60.1% (n = 101) 83.0% (n = 39)
In-hospital death 47.6% (n = 80) 63.8% (n = 30) 0.049
Renal replacement therapy 41.1% (n = 69) 59.6% (n = 28) 0.024
  1. P-value ≤ 0.05 was defined as statistically significant and presented as bold
  2. LOS, length of stay; PCT, procalcitonin; SAPS, simplified acute physiology score; IL-6, interleukin-6; ECMO, extra-corporeal membrane oxygenation; ARDS, acute respiratory distress syndrome; IQR, inter quartile range