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Fig. 1 | Critical Care

Fig. 1

From: Immune effects of PI3K/Akt/HIF-1α-regulated glycolysis in polymorphonuclear neutrophils during sepsis

Fig. 1

PMN transcriptomics revealed significant changes in glycolysis and mTOR/HIF-1α signaling pathway. a Heat map of DEGs identified by RNA-seq between patients with sepsis and healthy controls (P < 0.05). b Differential expression levels of glycolysis-associated genes in patients with sepsis versus those in healthy controls. c Histogram of KEGG enrichment analysis showing 22 significantly enriched pathways in patients with sepsis. KEGG ontology assignments were used to classify functional annotations of identified genes to elucidate their biological functions

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