Table 2 Global hemodynamic and tissue perfusion parameters before and 1 h after vitamin C infusion
From: Vitamin C improves microvascular reactivity and peripheral tissue perfusion in septic shock patients
Parameters, median (IQR) | H0 | H1 | p value |
|---|---|---|---|
Blood pressure (mmHg) | |||
Systolic | 107 (100–120) | 111 (102–121) | 0.43 |
Diastolic | 54 (51–61) | 58 (53–62) | 0.18 |
Mean | 71 (66–75) | 72 (66–77) | 0.07 |
Heart rate (/min) | 107 (101–111) | 107 (101–110) | 0.67 |
Mottling score | 1 (0–3) | 1 (0–2) | 0.06 |
Capillary refill time (s) | |||
Index | 2.1 (1.7–3.5) | 2 (1.2–3) | 0.0003 |
Knee | 3.7 (2.6–5.5) | 2.9 (1.9–4.7) | < 0.0001 |
Cardiac output (L/min) | 4.1 (3.3–4.5) | 4 (3.1–4.3) | 0.0376 |
Skin temperature | 31.2 (30.2–32.3) | 32.2 (31–33.7) | < 0.0001 |
Central-to-skin gradient temperature | 6.1 (4.9–7.4) | 4.6 (3.4–7.0) | < 0.0001 |
Norepinephrine dose (µg/kg min) | 0.6 (0.3–1.2) | 0.6 (0.3–1.1) | 0.46 |