Fig. 5

SROC curve of variation of end-tidal carbon dioxide for predicting fluid responsiveness. Each circle represents individual study estimates. The diamond is the summary point representing the average sensitivity and specificity estimates. The ellipses around this summary point are the 95% confidence region (dashed line) and the 95% prediction region (dotted line). The cutoff value of included studies: (1) Monge/2012 [16]: 5%; (2) Monnet/2013 [15]: 5%; (3) Zang/2013 [28]: 5%; (4) Wang/2015 [29]: 5%; (5) Toupin/2016 [30]: 2 mmHg; and (6) Yao/2016 [31]: 5.8%