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Table 2 Relative change in the concentration of the identified metabolites

From: Metabolomic diferences between COVID-19 and H1N1 influenza induced ARDS

Metabolite

IAP

COVID-19

P value

Relative change (%)

Fatty acids

73.57

85.22

0.0375

16

Isoleucine

3.41

2.88

0.1477

− 15

Valine

4.46

3.59

0.0237

− 19

Isobutyrate

0.09

0.09

0.9932

0

Methylsuccinate

0.14

0.12

0.6781

− 15

Alanine

5.60

5.29

0.6368

− 6

2-Hydroxybutyrate

4.50

2.31

0.0003

− 49

Lysine

1.44

1.65

0.7029

14

Acetate

1.81

1.93

0.8101

7

Proline

74.87

64.23

0.0049

− 14

Acetone

2.78

4.02

0.0424

45

Glutamate

4.66

7.15

0.0807

53

Glutamine

6.81

6.17

0.6102

− 9

Citrate

− 0.18

0.04

0.1807

− 123

Aspartate

0.43

0.19

0.0597

− 56

Methylguanidine

2.45

0.56

0.0041

− 77

Creatine

0.88

0.91

0.8831

3

Creatinine

0.76

0.57

0.0358

− 25

Choline

0.96

1.04

0.5691

9

Phosphocholine

1.27

1.42

0.2644

12

Glycerophosphocholine

2.61

2.72

0.6764

4

Glycerol

7.69

8.72

0.2456

13

Creatinine

0.45

1.39

0.0144

211

Lactate

8.80

11.10

0.0257

26

Glucose

5.86

9.42

0.0005

61

Tyrosine

0.34

0.12

0.0051

− 66

Phenylalanine

1.24

0.60

0.0619

− 52

  1. IAP, influenza A pneumonia
  2. Statistical significance was determined using a Bonferroni corrected Student’s t test assuming significant unequal corrected variance with p < 0.05
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