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Table 2 Functional outcomes at baseline and 6 months

From: The impact of COVID-19 critical illness on new disability, functional outcomes and return to work at 6 months: a prospective cohort study

 

Baseline

(n = 115)

6 months

(n = 115)

Absolute difference

(95% CI)

p value

Treatment for anxiety or depression—no. (%)

13/108 (12.0)

16/109 (14.7)

RD, 2.21 (− 3.75 to 8.20)

0.467

Unemployed due to health reasons—no. (%)

–

13/114 (11.4)

–

–

EQ-5D-5L

    

Utility score

1.0 (0.8–1.0)

0.8 (0.7–0.9)

MD, − 0.19 (− 0.28 to − 0.10)

 < 0.001

No problems with mobility

92/114 (80.7)

66/115 (57.3)

RD, − 23.92 (− 32.96 to − 14.87)

 < 0.001

New problems with mobility*

–

38/112 (33.9)

–

–

No problems with personal care

109/113 (96.5)

97/115 (84.3)

RD, − 12.00 (− 18.52 to − 5.50)

 < 0.001

New problems with personal care*

–

15/111 (13.5)

–

–

No problems with usual activities

106/113 (93.8)

64/115 (55.7)

RD, − 38.11 (− 47.79 to − 28.45)

 < 0.001

New problems with usual activities*

–

48/111 (43.2)

–

–

No problems with pain/discomfort

81/113 (71.7)

58/115 (50.4)

RD, − 21.06 (− 31.08 to − 11.06)

 < 0.001

New problems with pain/discomfort*

–

38/111 (34.2)

–

–

No problems with anxiety/depression

90/113 (79.6)

69/115 (60.0)

RD, − 19.26 (− 27.38 to − 11.16)

 < 0.001

New problems with anxiety/depression*

–

29/111 (26.1)

–

–

EuroQol-visual analogue scale

86.5 (75.0–95.0)

70.0 (60.0–85.0)

MD, − 15.00 (− 21.04 to − 8.95)

 < 0.001

Marital status

  

–

–

Never married

–

19/113 (16.8)

  

Currently married

–

65/113 (57.5)

  

Separated

–

3/113 (2.7)

  

Divorced

–

8/113 (7.1)

  

Widowed

–

9/113 (8.0)

  

Cohabiting

–

9/113 (8.0)

  

Financial distress**

1 (1–4)

1 (1–5)

MD, 0.00 (− 1.07 to 1.07)

0.999

WHODAS score, %

0.0 (0.0–4.2)

10.4 (2.1–22.9)

MD, 10.40 (7.06–13.77)

 < 0.001

Disability—no. (%)

7/112 (6.2)

25/112 (22.3)

RD, 16.01 (7.90–24.12)

 < 0.001

New disability—no. (%)

–

42/108 (38.9)

–

–

Category—no. (%)

    

No disability

89/112 (79.5)

44/112 (39.3)

COR, 11.22 (4.94–25.52)

 < 0.001

Mild disability

16/112 (14.3)

43/112 (38.4)

  

Moderate disability

7/112 (6.2)

19/112 (17.0)

  

Severe disability

0/112 (0.0)

6/112 (5.4)

  

Complete disability

0/112 (0.0)

0/112 (0.0)

  

IADL

–

8.0 (7.0–8.0)

–

–

Fully independent (IADL = 8)

–

66/94 (70.2)

–

–

HADS anxiety

–

3.0 (1.0–7.0)

–

–

Anxiety (HADS ≥ 8)

–

18/89 (20.2)

–

–

HADS depression

–

4.0 (1.0–7.0)

–

–

Depression (HADS ≥ 8)

–

18/89 (20.2)

–

–

IES-6 total

–

4.0 (1.0–9.0)

–

–

Mean score

–

0.7 (0.2–1.5)

–

–

Post-traumatic stress disorder (IES-6 mean > 1.75)

–

16/87 (18.4)

–

–

MoCA-BLIND

–

19.0 (17.0–20.0)

–

–

Cognitive dysfunction (MoCA-BLIND < 18)

–

24/72 (33.3)

–

–

  1. Data are median (quartile 25%–quartile 75%) or no (%). Percentages may not total 100 because of rounding
  2. CI confidence interval, COR common odds ratio where > 1.00 represents a higher chance of being in a worse category at 6 months compared to baseline, MD median difference, RD risk difference
  3. *New problems defined when the score of the specific component of EQ-5D-5L at 6 months was higher than at baseline
  4. **On a scale from 1 to 10 (1 would be the lowest level of financial distress)