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Table 2 Comparison of primary and secondary clinical outcomes between the treated and control groups

From: Effectiveness of anisodamine for the treatment of critically ill patients with septic shock: a multicentre randomized controlled trial

Variables

Total (n = 355)

Control (n = 174)

Treated (n = 181)

p value

Adjusted p value*

Hospital mortality, n (%)

117 (33)

62 (36)

55 (30)

0.348

0.621

ICU mortality, n (%)

72 (20)

39 (22)

33 (18)

0.397

0.621

ICU LOS, median (Q1, Q3)

5.74 (3.37, 10.46)

5.79 (3.34, 11.17)

5.6 (3.39, 9.8)

0.617

0.632

Hospital LOS, median (Q1, Q3)

11.62 (6.61, 18.51)

12.01 (7.63, 20.76)

10.83 (5.81, 16.65)

0.129

0.621

Duration of vasopressor use, median (Q1, Q3)

2.69 (1.61, 4.02)

2.74 (1.71, 4.05)

2.39 (1.31, 3.79)

0.216

0.621

CRRT days, median (Q1, Q3)

4.35 (2.97, 8.85)

3.45 (2.84, 8.1)

7.17 (4.35, 8.85)

0.435

0.621

MV duration, median (Q1, Q3)

5.05 (2.99, 9.9)

5.61 (3.62, 9.92)

4.84 (2.88, 9.75)

0.632

0.632

Vasopressor free days in 28 days, median (Q1, Q3)

25.23 (10.15, 28)

25.22 (8.6, 27.94)

25.23 (12.6, 28)

0.585

0.621

MV free in 28 days, median (Q1, Q3)

25.26 (7.18, 28)

24.37 (5.86, 28)

25.99 (8.47, 28)

0.411

0.621

CRRT free in 28 days, median (Q1,Q3)

28 (11.48, 28)

28 (10.22, 28)

28 (13.42, 28)

0.366

0.632

  1. MV mechanical ventilation, LOS length of stay, ICU intensive care unit, CRRT continuous renal replacement therapy, Q1 first quartile, Q3 third quartile
  2. *p values were adjusted for false discovery rate by the Benjamini–Hochberg method