Table 1 Main characteristics of our population

Age (years)

59.4 ± 14.78

65.37 ± 12.75*

0.04

61.5 ± 14.2

63.6 ± 14.6

0.292

Sex (male, %)

50.9

59.5

0.42

54.7

55.1

0.954

BMI (kg/m²)

25.62 ± 3.83

25.44 ± 2.9

0.8

24.93 ± 3.59

25.01 ± 2.9

0.865

SBP (mmHg)

133.88 ± 16.1

143.08 ± 19.3*

0.014

137.76 ± 19.5

142.2 ± 19.3

0.114

DBP (mmHg)

79.93 ± 9.5

84.38 ± 8.8*

0.025

84.46 ± 9.47

86.3 ± 14.9

0.239

Hypertension (%)

26.3

51.3*

0.013

39.9

44.8

0.493

Glycemia (mg/dl)

104.9 ± 22.2

112.2 ± 27.8

0.163

109.39 ± 28.2

112.48 ± 42.7

0.497

Diabetes (%)

7.0

21.6*

0.039

12.5

17.2

0.344

Dyslipidemia (%)

24.5

43.2

0.059

30.8

34.4

0.586

Smoking (current/past, %)

14/22.8

21.6/37.8*

0.032

18.2/26.6

12.1/34.4^#

0.081

D-dimer (µg/ml)

2.35 ± 1.73

3.52 ± 0.95*

0.001

2.80 ± 1.68

3.18 ± 1.83

0.120

IL-6 (pg/ml)

1.7 ± 1.1

4.0 ± 2.8*

0.002

7.5 ± 4.0^#

8.4 ± 5.5^#

0.121

TNFα (pg/ml)

4.5 ± 2.3

6.0 ± 4.7*

0.035

6.5 ± 4.2

5.8 ± 4.7

0.271

hs-CRP (µg/ml)

2.15 ± 1.1

2.6 ± 1.16

0.07

3.6 ± 3.2^#

4.2 ± 2.9^#

0.144

EC-EV miR-24 (copies/10 nl)

30.5 ± 14.6

29.85 ± 15.5

0.827

26.64 ± 20.9^#

15.41 ± 14.7*^,#

0.001