Table 2 Univariable and multivariable model assessing the association of baseline driving pressure and mechanical power with 28-day mortality
Univariable model | Multivariable model for ΔP | Multivariable model for MP | Multivariable model for ΔP and MP | |||||
|---|---|---|---|---|---|---|---|---|
Hazard ratio (95% CI) | p value | Hazard ratio (95% CI) | p value | Hazard ratio (95% CI) | p value | Hazard ratio (95% CI) | p value | |
Demographic characteristics | ||||||||
Age | 1.87 (1.58–2.21) | < 0.001 | 1.89 (1.58–2.25) | < 0.001 | 1.91 (1.60–2.28) | < 0.001 | 1.91 (1.61–2.28) | < 0.001 |
Co-existing disorders | ||||||||
COPD | 1.81 (1.22–2.68) | 0.003 | 1.70 (1.14–2.53) | 0.009 | 1.78 (1.20–2.66) | 0.004 | 1.79 (1.20–2.68) | 0.004 |
Laboratory tests at day 01 | ||||||||
pH | 0.68 (0.60–0.76) | < 0.001 | 0.75 (0.65–0.87) | < 0.001 | 0.77 (0.66–0.89) | < 0.001 | 0.77 (0.66–0.89) | < 0.001 |
Vital signs at day 01 | ||||||||
Heart rate | 1.23 (1.08–1.41) | 0.001 | 1.17 (1.01–1.35) | 0.031 | 1.16 (1.01–1.34) | 0.035 | 1.16 (1.01–1.34) | 0.037 |
Ventilatory variables at day 01 | ||||||||
Driving pressure | 1.09 (0.96–1.24) | 0.190 | 1.10 (0.97–1.24) | 0.147 | – | – | 1.02 (0.88–1.18) | 0.750 |
Absolute mechanical power | 1.17 (1.02–1.33) | 0.020 | – | – | 1.18 (1.04–1.35) | 0.009 | 1.17 (1.01–1.36) | 0.031 |