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Table 1 ECLS and drowning

From: Treatment of the lung injury of drowning: a systematic review

Study

Outcome measured

Outcome

Confounders

Drowning

   

Steiner et al. [25]

Mortality

3/8 (37.5%) survived

No validated assessment tool used for neurological outcome

Weber et al. [27]

Mortality

Neurological outcome

1/4 (25.0%) survived

No validated assessment tool used for neurological outcome

Kim et al. [47]

Mortality

Neurological outcome

8/9 (88.9%) rapidly worsening ARDS

7/9 (77.8%) survived

7/9 (77.8%) good neurological outcome

No validated assessment tool used for neurological outcome

Burke et al. [21]

Mortality

60/84 (71.2%) survived (no cardiac arrest prior to ECLS)

49/86 (56.9%) survived (cardiac arrest followed by ROSC prior to ECLS)

18/77 (23.3%) survived (ECPR)

No neurologic outcome reported

Watson et al. [26]

Mortality

3/4 (75%) survival

No neurologic outcome reported

Lee et al. [37]

Mortality

15/18 (83.3%)

No neurologic outcome reported

Drowning + Hypothermia

   

Saltiel et al. [22]

Mortality

Neurological outcome

2/3 (66.6%) survived, 1/3 (33.3%) GNO

No validated assessment tool used for neurological outcome

Walpoth et al. [34]

Mortality

Neurological outcome

0/2 (0.0%) survived

No validated assessment tool used for neurological outcome

Mair et al. [48]

Mortality

Neurological outcome

1/7 (14.3%) survived

No validated assessment tool used for neurological outcome

Farstad et al. [45]

Mortality

1/14 (7%) survived

Neurological data presented as group results

Wollenek et al. [51]

Mortality

Neurological outcome

2/3 (66.6%) survived

1/3 (33.3%) poor neurological outcome

1/3 (33.3%) good neurological outcome

No validated assessment tool used for neurological outcome

Eich et al. [44]

Mortality

Neurological outcome

USFD

5/12 (42%) survived

2/12 (17%) full recovery (PCPC 1)

3/12 (25%) (PCPC 5)

Paediatric cerebral performance category

Scaife et al. [23]

Mortality

Neurological outcome

1/5 (20%) survived

No validated assessment tool used for neurological outcome

Coskun et al. [43]

Mortality

Neurological outcome

5/13 (38%) survived

3/13 (23%) severe neurological deficit

No validated assessment tool used for neurological outcome

Suominen et al. [49]

Mortality

Neurological outcome

1/9 (11%) survived

No validated assessment tool used for neurological outcome

Wanscher et al. [35]

Mortality

Neurological outcome

7/7 (100%) survived

GOSE ranged from 3–7

Group results given for neurological outcome

Skarda et al. [24]

Mortality

Neurological outcome

0/7 (0%) survived

 

Champigneulle et al. [31]

Mortality

Neurological outcome

USFD

2/20 (10%) survived

1 good neurological outcome (CPC 1)

1 severe cerebral disability (CPC 3)

Validated neurological outcome score used

Weuster et al. [50]

Mortality

Neurological outcome

Drowning definition

2/9 (22%) survived

2/9 GNO

No validated assessment tool used for neurological outcome

Khorsandi et al. [46]

Mortality

3/4 survived

No neurologic outcome reported

Bauman et al. [20]

Mortality

Neurological outcome

3/5 survived

No validated assessment tool used for neurological outcome

  1. ECLS, Extra-corporeal life support; GNO, good neurological outcome; ROSC, return of spontaneous circulation; ECPR, ECLS-assisted cardio-pulmonary resuscitation; PCPC, paediatric cerebral performance category; GOSE, Glasgow Outcome Scale Extended; USFD, Utstein Style for Drowning; CPC, cerebral performance category