A quantitative analysis of extension and distribution of lung injury in COVID-19: a prospective study based on chest computed tomography

Table 2 Descriptive statistics of COVID-19 patients underwent chest CT

	Total		The day of CT		p
	Median	IQR	Median	IQR	p
Days of invasive mechanical ventilation	7	16	4	11	0.15

Laboratory analysis	At arrival		The day of CT		p
Laboratory analysis	Median	IQR	Median	IQR	p
C-reactive protein [mg/mL]	200	131	202	209	0.69
Leukocytes [10³/mL]	9	3	11	10	0.09
Procalcitonin [ng/mL]	1.10	1.44	1.00	2.30	0.75
Interleukin-6 (IL-6) [pg/mL]	166	167	107	122	0.33
Ferritin [µg/L]	1457	1685	1094	1984	< 0.01*
D-dimer [ng/mL]	1.95	1.63	2.45	3.83	< 0.01*
Creatinine [umol/mL]	89	44	102	133	< 0.01*
Glomerular filtration rate (creatinine) [mL/min/1.73 m²]	64	30	57	57	< 0.01*
P/F ratio [mmHg]	104	75	164	50	< 0.01*
PCO₂ [mmHg]	33	9	42	12	< 0.01*
pH	7.48	0.05	7.43	0.15	0.01*
Respiratory rate (breath per minutes)	31	13	23	7	< 0.01*

Respiratory mechanics	The day of CT
Respiratory mechanics	Median	IQR
Highest Vt/kg PBW	6.8	0.9
Highest minute ventilation [L/min]	11.7	3.6
PEEP [cmH₂O]	12	4
Lowest static compliance [mL/cmH₂O]	38	25
Highest plateau pressure [cmH₂O]	14	7
Highest peak pressure [cmH₂O]	22	6

		Median	IQR
Days of noninvasive ventilation	(5 out 23 patients)	1.5	2

Data were reported as median values (IQR) or numerosity (%). Wilcoxon rank sum test to detect statistical differences (a = 0.05, * to mark statistical significant differences)

ISSN: 1364-8535