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Table 2 Advantages and disadvantages of each renal replacement modality during extracorpo-real membrane oxygenation (ECMO)

From: Acute kidney injury in ECMO patients

Modality

Advantages

Disadvantages

IHD

Integration in ECMO circuit possible

Reduced filter downtime

Lower costs than CRRT

Need for more rapid fluid removal

Risk of hemodynamic instability

Disequilibrium syndrome

PIRRT

Integration in ECMO circuit possible

Reduced filter downtime

Lower costs than CRRT

Slower volume and solute removal than IHD

Risk of hemodynamic instability in high-risk patients

CRRT

Integration in ECMO circuit possible

Continuous fluid and solute removal

Allows more precise control of fluid balance

Better hemodynamic stability

Patient immobilization

Increased risk of hypothermia

High costs

PD

Better hemodynamic stability

Technically simple

Lower cost

No addition of anticoagulation

Less experience in adult patients

Requires specific intraperitoneal catheters

Risk of peritonitis

Risk of hyperglycemia

May interfere with diaphragmatic movements

  1. IHD intermittent hemodialysis, PIRRT prolonged intmeromviettmenetn thsemodialysis, CRRT continuous renal replacement therapy, PD peritoneal dialysis