Early individualized positive end-expiratory pressure guided by electrical impedance tomography in acute respiratory distress syndrome: a randomized controlled clinical trial

Table 1 Baseline clinical characteristics and demographics of patients

Variables	EIT group (n = 61)	Control group (n = 56)	p values
Age (years)	61.0 (44.0, 68.0)	66.5 (50.0, 73.0)	0.074
Female Sex	19/61	21/56	0.597
Body mass index (kg/m²)	26.0 (22.9, 29.1)	26.0 (22.9, 28.6)	0.933
APACHE II score	19.0 (15.0, 25.0)	18.0 (15.0, 21.2)	0.568
Reason for ARDS
Pneumonia	28/61	24/56	0.884
Extrapulmonary sepsis	10/61	15/56	0.252
Severe acute pancreatitis	0/61	1/56	0.972
Post-cardiac operation	14/61	8/56	0.231
Others	9/61	8/56	0.848
Mild ARDS	18/61	23/56	0.292
Moderate ARDS	28/61	25/56	0.960
Severe ARDS	15/61	8/56	0.161
Other parameters
Heart rate	98.0 (86.0, 113.0)	103.0 (88.2, 120.8)	0.287
Mean arterial pressure	82.0 (73.0, 94.0)	87.5 (75.8, 99.2)	0.242
Received NE (n, %)	53/61 (86.9%)	53/56 (94.6%)	0.151
NE dose (ug/kg/min)	0.1 (0.0, 0.3)	0.1 (0.1, 0.2)	0.715
ScvO₂ (%)	73.7 (71.0, 81.7)	76.2 (68.7, 81.6)	0.953
Pv-a CO₂ (mmHg)	4.6 (2.6, 6.6)	4.3 (2.4, 7.0)	0.923
Arterial lactate (mmol/L)	2.2 (1.4, 4.7)	2.0 (1.4, 4.0)	0.550
White blood cell (10^⁹/L)	9.8 (8.6, 11.3)	10.3 (8.8, 12.8)	0.287

ARDS, acute respiratory distress syndrome; NE, norepinephrine; ScvO₂, central venous oxygen saturation; Pv-a CO₂, venous-to-arterial carbon dioxide difference; APACHE II, Acute Physiology and Chronic Health Evaluation

ISSN: 1364-8535