Table 1 Demographic data. Data were available for all the patients, unless indicated by N. Quantitative data are expressed as Medians (interquartile range)
|  | LPS | UHG | Sites combined | Sepsis-2 N = 260 | Sepsis-3 N = 144 |
|---|---|---|---|---|---|
Clinical characteristics | |||||
 Female (No. %) | 404 (48.3%) | 276 (40.6%) | 680 (44.8%) | 101 (38.9%) | 46 (31.9%) |
 Male (No. %) | 433 (51.7%) | 404 (59.4%) | 837 (55.2%) | 159 (61.2%) | 98 (68.1%) |
 Age, years | 57 (39–71) | 72 (60–80) | 64 (47–76) | 66 (51–77) | 72 (61–80) |
 Temperature (°C) N = 1506 | 36.6 (36.2–37.0) | 36.2 (36.0–36.7) | 36.5 (36.0–36.9) | 37.1 (36.5–38.2) | 36.8 (36.2–38.0) |
 Heart rate (beats/min) | 85 (73–100) | 82 (70–98) | 84 (71–99) | 100 (92–110) | 93 (75–106) |
 Respiratory (breaths/min) N = 865 | 20 (16–22) | 18 (16–24) | 19.0 (16–24) | 22 (18–26) | 23 (18–26) |
 Immunosuppression | 38 (4.5%) | 101 (14.9%) | 139 (9.2%) | 38 (14.6%) | 22 (15.3%) |
Laboratory parameters | |||||
 WBC (1 × 103/μL) | 8.33 (6.24–10.94) | 9.17 (6.86–11.89) | 8.71 (6.50–11.34) | 13.02 (9.02–16.28) | 10.82 (8.27–15.03) |
 PMN (1 × 103/μL) | 5.80 (3.88–8.44) | 6.74 (4.73–9.42) | 6.27 (4.23–8.90) | 10.65 (7.09–14.04) | 8.99 (6.15–13.18) |
 EO (1 × 103/μL) | 0.07 (0.02–0.15) | 0.07(0.02–0.14) | 0.07 (0.02–0.14) | 0.02 (0.01–0.06) | 0.02 (0.0–0.06) |
 MDW (U) | 19.28 (17.85–21.68) | 21.09 (19.19–24.03) | 20.15 (18.22–22.79) | 23.92 (21.54–26.94) | 24.61 (22.33–28.47) |
 PCT (ng/mL) | 0.04 (0.02–0.10) | 0.06 (0.02–0.24) | 0.05 (0.02–0.15) | 0.21 (0.07–0.79) | 0.34 (0.13–1.54) |
 CRP (mg/L) | 5.22 (0.85–31.76) | 18.30 (4.75–82.50) | 10.10 (1.91–52.89) | 82.50 (36.90–185.50) | 95.35 (44.13–197.98) |
 CREAT (μmol/L) N = 1489 | 76.00 (64.00–95.00) | 80.40 (62.80–113.20) | 78.00 (63.60–102.00) | 84.00 (65.40–123.00) | 115.35 (74.30–186.50) |