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Table 2 Quantitative lung dual-energy computed tomography parameters

From: Lung distribution of gas and blood volume in critically ill COVID-19 patients: a quantitative dual-energy computed tomography study

Parameter All (N = 35) Non-invasive (N = 12) Invasive (N = 23) p
Lung volume (mL) 2794 [2150 to 3690] 3680 [3180 to 4245] 2359 [1934 to 3207] 0.001
Mean attenuation (HU) − 615 [− 687 to − 454] − 771 [− 807 to − 649] − 506 [− 639 to − 406]  < 0.001*
Lung weight§ (g) 1039 [878 to 1268] 966 [759 to 1061] 1086 [884 to 1283] 0.045*
Pulmonary gas volume (mL) (Vgas) 1621 [1019 to 2498] 2929 [1873 to 3350] 1140 [726 to 1765]  < 0.001*
Evidence of macroscopic pulmonary embolism, n (%) 6 (17.1) 1 (8.0) 5 (21.7) 0.640
Non-perfused tissue (g) 138 [90 to 219] 118 [87 to 201] 180 [102 to 262] 0.327
Dead-space tissue (g) 87 [57 to 162] 87 [71 to 142] 86 [51 to 171] 0.503
Non-aerated/non-perfused lung tissue (g) 33 [12 to 84] 11 [3 to 21] 65 [29 to 105] 0.001*
Shunt tissue (g) 193 [70 to 299] 39 [20 to 128] 253 [180 to 357] < 0.001*
Tissue with gas:blood volume ratio < 1 (g) 360 [292 to 435] 429 [325 to 464] 355 [291 to 423] 0.195
Tissue with gas:blood volume ratio > 1 (g) 293 [249 to 355] 295 [273 to 328] 293 [248 to 365] 0.932
  1. HU hounsfield units
  2. *Non-invasive versus invasive respiratory support (p < 0.05)
  3. §Lung weight measured without considering blood vessels; thus, values are lower compared to conventional quantitative computed tomography analysis