Table 2 Quantitative lung dual-energy computed tomography parameters
Parameter | All (N = 35) | Non-invasive (N = 12) | Invasive (N = 23) | p |
|---|---|---|---|---|
Lung volume (mL) | 2794 [2150 to 3690] | 3680 [3180 to 4245] | 2359 [1934 to 3207] | 0.001 |
Mean attenuation (HU) | − 615 [− 687 to − 454] | − 771 [− 807 to − 649] | − 506 [− 639 to − 406] | < 0.001* |
Lung weight§ (g) | 1039 [878 to 1268] | 966 [759 to 1061] | 1086 [884 to 1283] | 0.045* |
Pulmonary gas volume (mL) (Vgas) | 1621 [1019 to 2498] | 2929 [1873 to 3350] | 1140 [726 to 1765] | < 0.001* |
Evidence of macroscopic pulmonary embolism, n (%) | 6 (17.1) | 1 (8.0) | 5 (21.7) | 0.640 |
Non-perfused tissue (g) | 138 [90 to 219] | 118 [87 to 201] | 180 [102 to 262] | 0.327 |
Dead-space tissue (g) | 87 [57 to 162] | 87 [71 to 142] | 86 [51 to 171] | 0.503 |
Non-aerated/non-perfused lung tissue (g) | 33 [12 to 84] | 11 [3 to 21] | 65 [29 to 105] | 0.001* |
Shunt tissue (g) | 193 [70 to 299] | 39 [20 to 128] | 253 [180 to 357] | < 0.001* |
Tissue with gas:blood volume ratio < 1 (g) | 360 [292 to 435] | 429 [325 to 464] | 355 [291 to 423] | 0.195 |
Tissue with gas:blood volume ratio > 1 (g) | 293 [249 to 355] | 295 [273 to 328] | 293 [248 to 365] | 0.932 |