Table 2 Comparison of respiratory and hemodynamic variables of COVID-19 and non-COVID-19 acute respiratory distress syndrome

Respiratory characteristics at baseline

PaO₂/FiO₂ (mmHg)

129 (97–175)

138 (96–172)

TV (mL/kg PBW)

6.0 (5.7–6.1)

6.0 (5.7–6.3)

PEEP (cmH₂O)

13 (10–15)

12 (10–15)

Driving pressure (cmH₂O)

13 (11–15)

13 (9–17)

Crs (mL/cmH₂O)

31 (25–38)

31 (24–44)

Maximal/minimal values of respiratory characteristics during TPTD monitoring

PaO₂/FiO_2min (mmHg)

81 (70–109)

100 (80–124)

PEEP_max (cmH₂O)

15 (12–16)

14 (12–16)

DP_max (cmH₂O)

16 (15–18)

16 (12–21)

Crs_min (mL/cmH₂O)

25 (21–28)

23 (16–36)

Hemodynamic variables and CRP at baseline

CI (L/min/m²)

2.8 (2.1–3.5)

2.8 (2.5–4.2)

GEDVi (mL/m²)

728 (588–824)

696 (585–824)

EVLWi (mL/kg)

17 (14–21)

15 (11–19)

PVPI

3.5 (2.9–4.5)

2.8 (2.2–3.7)

GEF (%)

20 (15–24)

18 (15–23)

NE (µg/kg/min)

0.32 (0.13–0.63)

0.74 (0.49–1.45)

Lactate (mmol/L)

1.6 (1.3–2.1)

2.2 (1.2–3.5)

CRP (mg/L)

218 (146–295)

248 (125–321)

Maximal/minimal values of hemodynamic variables and CRP during TPTD monitoring

CI_min (L/min/m²)

2.4 (2.0–2.8)

2.5 (2.0–3.0)

GEDVi_min (mL/m²)

634 (548–752)

600 (538–712)

EVLWi_max (mL/kg)

24 (18–27)

21 (15–24)

PVPI_max

4.6 (3.8–5.7)

4.1 (3.3–4.8)

GEF_min (%)

16 (13–19)

15 (11–19)

NE_max (µg/kg/min)

0.51 (0.16–0.89)

1.01 (0.52–1.74)

Lactate_max (mmol/L)

2.0 (1.6–2.7)

2.7 (2.1–4.3)

Fluid balance (mL/day)

1016 (235–1844)

1033 (436–1715)