Table 1 Baseline characteristics
Control group N = 89 | Diuretic group N = 77 | |
|---|---|---|
Age | 66 [60–74] | 66 [58–72] |
Sex ratio F/M | 28(31.5%)/61(68.6%) | 16(20.8%)/61(79.2%) |
SAPS II | 53 [45–59] | 52 [41–58] |
SOFA baseline | 7 [5–10] | 8 [6–10] |
SOFA at randomization | 4 [2–6] | 4 [3–5] |
Height (cm) | 169 [163–175] | 171 [163–175] |
Weight at baseline (kg) | 76 [64–85] | 82 [68–92] |
Weight at randomization (kg) | 84 [75–97] | 88.5 [73–99] |
MV before randomization (days) | 5 [4–8] | 6 [4–8] |
BMI | 25.5 [22.6–29.2] | 28.4 [25.5–34.5] |
Hypertension | 13 (14.6%) | 5 (6.5%) |
Chronic respiratory disease | 10 (11.2%) | 5 (6.5%) |
Chronic kidney disease | 3 (3.4%) | 1 (1.3%) |
Use of diuretics | 11 (12.4%) | 8 (10.4%) |
Diabetes mellitus | 9 (10.1%) | 11 (14.3%) |
Active smoking | 21 (23.6%) | 14 (18.2%) |
Admission | ||
Sepsis/septic shock | 28 (31.4%) | 21 (27.2%) |
Acute respiratory failure | 42 (47.2%) | 33 (42.9%) |
Trauma | 7 (7.9%) | 6 (7.8%) |
Hemorrhagic shock | 5 (5.6%) | 4 (5.2%) |
Elective surgery | 1 (1.1%) | 4 (5.2%) |
Misc | 6 (6.8%) | 9 (11.7%) |
RRT/AKI before randomization | 27 (30.3%) | 21 (27.3%) |