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Fig. 2 | Critical Care

Fig. 2

From: Identification and characterization of neutrophil heterogeneity in sepsis

Fig. 2

scRNA-seq uncovers neutrophil transcriptional heterogeneity after LPS stimulation. a UMAP representation of gene expression data in 9421 neutrophils, including the control and LPS-stimulated cells. b Seurat cluster assignment projected onto the UMAP plot. c The proportion of each subset of cells in the control group and the LPS stimulation group. d PD-L1 and MHC-II components (H2-Ob, H2-Eb, H2-Ab1, H2-Aa) expression in different clusters. e Bar plot showing the changes in the proportions of neutrophils expressing PD-L1 or MHC-II components (H2-Ab1) in each cluster. f Heat map of significant differential gene in each cluster. g Pseudotime map showed changes in neutrophil differentiation after LPS stimulation

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