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Fig. 4 | Critical Care

Fig. 4

From: Sepsis is associated with mitochondrial DNA damage and a reduced mitochondrial mass in the kidney of patients with sepsis-AKI

Fig. 4

Changes in mitochondrial biogenesis, fusion, fission and mitophagy after 48-h LPS induction in HUVECs. Cells were induced with 10 µg/mL LPS for 48 h. mRNA expression of a mnSOD, b NRF2, c TFAM, d DRP1, e MFN2, and f PINK1; g Relative mtDNA damage levels of control and LPS-induced HUVECs. Bars represent median, dots represent individual levels; * means p < 0.05 and ** p <0.005

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Critical Care

ISSN: 1364-8535