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Table 1 SARS-CoV-2 and receptor binding

From: SARS-CoV-2 pneumonia—receptor binding and lung immunopathology: a narrative review

Mechanisms of SARS-CoV-2 receptor binding
SARS-CoV-2: similar receptor-binding domain structure to SARS-CoV [20]
SARS-CoV-2 uses angiotensin-converting enzyme 2 to target cells [1]
SARS-CoV-2 and SARS-CoV S protein affinity to angiotensin-converting enzyme 2: similar [21] or ~ 10- to 20-fold higher [22]
SARS-CoV-2 S protein: requires transmembrane protease serine 2 for S protein priming [26]
SARS-CoV-2 S protein: furin-like protease recognition pattern [25]
Soluble recombinant human ACE2 can inhibit SARS-CoV-2 infections [27]
COVID 19 patients: Greater number of angiotensin-converting enzyme 2-positive lung endothelial cells compared with uninfected controls [29]