Fig. 1
From: Dosing of thromboprophylaxis and mortality in critically ill COVID-19 patients
Kaplan–Meier plots of outcomes by initial dosing strategy of thromboprophylaxis. Kaplan–Meier plot of a 28-day survival, b thromboembolic events, and c bleeding events, among 152 patients admitted to the ICU due to COVID-19 between March 6 and April 30, 2020. By thromboprophylactic anticoagulant strategy with tinzaparin/dalteparin: The red line represent low-dose thromboprophylaxis (2500–4500 IU of tinzaparin daily, or 2500–5000 IU of dalteparin daily), the blue line represent medium-dose thromboprophylaxis (> 4500 IU to < 175 IU/kg of body weight of tinzaparin daily, or > 5000 IU to < 200 IU/kg of body weight of dalteparin daily), and the black line represent high-dose thromboprophylaxis (≥ 175 IU/kg of body weight of tinzaparin daily, or ≥ 200 IU/kg of body weight of dalteparin daily). Thromboembolic events in b are defined as pulmonary embolism, deep vein thrombosis, ischemic stroke, or peripheral arterial embolism. Hemorrhagic events in c are defined as grade 1–4 in the WHO bleeding scale