Skip to main content
Fig. 5 | Critical Care

Fig. 5

From: Xenon treatment after severe traumatic brain injury improves locomotor outcome, reduces acute neuronal loss and enhances early beneficial neuroinflammation: a randomized, blinded, controlled animal study

Fig. 5

Xenon treatment enhances early microglial proliferation. a Typical immunostaining showing Iba1 (green) staining from sham, TBI control and TBI xenon animals in left hypothalamus. The scale bar is 50 μm and applies to all images. b Quantification of Iba1-positive cells from sham (white bars), TBI control (blue bars) and TBI xenon (red bars) in i motor/medial parietal association cortex (M1/MPtA) & contusional cortex, ii somatosensory cortex (S1BF), iii retrosplenial cortex (RSC) iv hypothalamus, v amygdala, vi hippocampal CA1, vii CA2, viii CA3, ix dentate gyrus (DG) and x corpus callosum. * p < 0.05, ** p < 0.01, compared to sham group as indicated by brackets, Kruskal Wallis test with Benjamini Yekutieli correction. n = 6 sham (white boxes) 24 h, n = 6, TBI control 24 h (blue boxes); n = 5 TBI xenon 24 h (red boxes)

Back to article page

Critical Care

ISSN: 1364-8535