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Fig. 2 | Critical Care

Fig. 2

From: Xenon treatment after severe traumatic brain injury improves locomotor outcome, reduces acute neuronal loss and enhances early beneficial neuroinflammation: a randomized, blinded, controlled animal study

Fig. 2

Neuronal loss was quantified in coronal brain sections. Image shows a typical section at Bregma -3.12 mm from a xenon-treated TBI animal at 24 h, stained with the neuronal marker NeuN (yellow) and nonspecific nuclear marker DAPI (red). The contusion is visible in the right hemisphere motor area (left of image). Neurons were counted in the left and right retrosplenial cortex (RSC) in layers 1, 234, 5 & 6; the left motor/medial parietal association cortex (M1/MPtA) in layers 1, 23, 4, 5 & 6; left and right somatosensory cortex (S1BF) in layers 1, 23, 4, 5 & 6; and in the right and left subcortical regions of hippocampus (CA1; CA2; CA3 & DG), amygdala (Amyg) and ventromedial hypothalamus (VMH). The scale bar is 1000 μm

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Critical Care

ISSN: 1364-8535