Table 1 Baseline characteristics

Clinical characteristics

Mean age (years) (SD)

46.8 ± 11.5

56.4 ± 16.8

55.2 ± 16.5

0.28^a

Male sex (n, %)

1 (20%)

21 (58.3%)

22 (53.7%)

0.16^b

Median SOFA score (IQR)

1 (1)

2 (1–3)

2 (1–2)

0.09^b

Median duration of symptoms (IQR)

6 (4–7)

7 (5–8)

7 (5–8)

0.44^a

Mean Pa/Fi ratio (SD)

397 ± 37.7

294 ± 111.3

307 ± 110.2

0.035^a

Mean D-Dimer levels (ng/mL) (SD)

378 ± 60.2

1156 ± 1018.1

1057 ± 984.1

 < 0.01

Computed tomography findings

Predominant pattern (n, %)

Ground-glass opacities

5 (100%)

18 (50%)

23 (56.1%)

0.21^b

Mixed pattern with predominant ground-glass opacities

0 (0%)

10 (27.8%)

10 (24.4%)

Mixed pattern with predominant consolidation

0 (0%)

8 (22.2%)

8 (19.5%)

Median number of compromised lobes (IQR)

4 (2–5)

5(5)

5(5)

0.02^a

Pleural effusion (n, %)

2 (40%)

5 (13.9%)

7 (17.1%)

0.20^b

Pulmonary embolism (n, %)

0 (0%)

2 (5.6%)

2 (4.8%)

1.0^b

Right ventricular overload (n, %)

0 (0%)

0 (0%)

0 (0%)

–

Vascular dilatation (n, %)

4 (80%)

36 (100%)

40 (97.5%)

0.12^b

Median number of lobes with vascular dilatation (IQR)

2 (2)

3.5 (2–5)

3 (2–5)

0.17^a

Vascular tortuosity (n, %)

0 (0%)

14 (38.9%)

14 (34.2%)

0.15^b

Median CT severity score (IQR)

3 (2–5)

7 (5–10)

7 (5–10)

0.01^b