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Table 1 Patient anthropometric characteristics, comorbidities and clinical parameters at EBP initiation

From: Blood purification therapy with a hemodiafilter featuring enhanced adsorptive properties for cytokine removal in patients presenting COVID-19: a pilot study

Anthropometric data

Comorbidities

Ethnicity

CKD

3 (8.1%)

 Caucasian

35 (94.6%)

CLD (Child-Pugh ≥ B)

1 (2.7%)

 Asian

2 (5.4%)

Diabetes

8 (21.6%)

Gender

Previous oncological disease

3 (8.1%)

 Male

31 (83.8%)

Hypertension

11 (29.7%)

 Female

6 (16.2%)

Cerebral vascular disease

1 (2.7%)

 M/F

31/6

Coronary vascular disease

1 (2.7%)

Age (years)

59.5 ± 9.5

Systemic vascular disease

1 (2.7%)

Weight (Kg)

90 ± 19

Chronic steroid tt

1 (2.7%)

Height (cm)

171 ± 8

Obesity

20 (54.1%)

BMI

30.3 (5.7)

Other

13 (35.1%)

Clinical data at RRT initiation

GCS

Lactates (mmol/L)

1.67 (1.2)

 3

36 (97.3%)

Sodium (mmol/L)

138 (10)

 4

1 (2.7%)

Potassium (mmol/L)

4.4 ± 0.7

Heart rate (bpm)

91 ± 21

Magnesium (mg/dL)

2.3 ± 0.7

Rhythm

Phosphate (mg/dL)

4.7 ± 1.8

 Rhythmic

31 (83.8%)

Bicarbonate (mEq/L)

23 ± 5

 Arrhythmic

6 (16.2%)

Hematocrit (%)

33.8 ± 7.4

Systolic pressure (mmHg)

120 (30)

Baseline creatinine (mg/dL)

0.89 (0.2)

Diastolic pressure (mmHg)

63 ± 12

Current creatinine (mg/dL)

2.26 (2.5)

Mean pressure (mmHg)

84 (23)

Urinary output (ml/h)

30 (40)

Vasoactive

24 (64.9%)

24 h urinary output (ml)

1000 (1250)

 Adrenaline

2 (5.4%), 0.03 ± 0.01 μg/kg/min

Urea (mg/dL)

71 (139)

 Noradrenaline

24 (64.9%), 0.20 ± 0.19 μg/kg/min

Bilirubin (mg/dl)

0.8 (2.5)

 Vasopressin

1 (2.7%), 1.6 U/h

Albumin (g/dl)

2.64 (0.42)

 Dobutamine

1 (2.7%), 8 μg/kg/min

Platelets (10^3/μl)

231 (177)

 Dopamine

1 (2.7%), 3 μg/kg/min

INR

1.1 (0.3)

Vasoactive Inotropic Score (VIS)

10 (22)

Antithrombin (%)

71 ± 26

VT settings (ml)

459 ± 63

Fibrinogen (mg/dl)

640 (229)

 RR (breaths/min)

23 ± 4

D-dimers (ng/ml)

3240 (8417)

 PEEP (cmH2O)

13 ± 3

PCT (ng/ml)

0.78 (2.59)

PIP (cmH2O)

30 (9)

Temp (°C)

36.7 ± 0.9

Mean airway pressure (cmH2O)

30

CRP (mg/L)

200 (176)

PPlat (cmH2O)

26 ± 3

WBC (10^3/μl)

10.47 (6.73)

Compliance

39 ± 12

Ferritin (ng/ml)

12.3 ± 5.9

FiO2 (%)

70 (19)

IL-6 (ng/l)

1230 (895)

PaO2

83 ± 23

CD 4+

164.9 ± 122.5

PaO2/FiO2

119 ± 42

Crystalloid prev.12 h (ml)

906 ± 693

SaO2 (%)

95 (3)

APACHE IV

117 ± 20

PaCO2 (mmHg)

51 ± 11

Predicted mortality (%)

64.7 ± 16.2

A-a O2 gradient

377.7 ± 113.1

Total SOFA Score

13 (6)

pH

7.31 ± 0.10

  
  1. CKD chronic kidney disease, CLD chronic liver disease, CRP C-reactive protein, INR international normalized ratio, MV mechanical ventilation, OTI oro-tracheal intubation, PCT procalcitonin, PIP peak inspiratory pressure, Pplat plateau pressure, RR respiratory rate, VT tidal volume, WBC white blood cells