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Table 2 Bodyweight, dose of infused bacteria, and in vivo blood bacterial counts

From: Mode of bacterial killing affects the inflammatory response and associated organ dysfunctions in a porcine E. coli intensive care sepsis model

Variable Cefuroxime Live E. coli Heat Cefuroxime + tobramycin
Bodyweight (kg) 26.0 ± 2.0 24.7 ± 1.4 26.6 ± 1.5 25.5 ± 2.7
Infused bacteria, total dose (log10 CFU) 8.78 ± 0.06 8.78 ± 0.07a 8.71 ± 0.05 8.74 ± 0.05
Infused bacteria, live bacterial dose (log10 CFU) 5.50 ± 0.40 8.78 ± 0.07 0.85 ± 1.70 2.39 ± 1.70
Blood bacterial count in vivo (log10 CFU × ml−1) 0 h < 0.5 < 0.5 < 0.5 < 0.5
1 h < 0.5 2.83 ± 0.38 < 0.5 < 0.5
2 h < 0.5 3.18 ± 0.48 < 0.5 < 0.5
3 h < 0.5 3.30 ± 0.53 < 0.5 < 0.5
4–6 h < 0.5 < 0.5 < 0.5 < 0.5
  1. Mean ± SD; CFU colony-forming unit
  2. aThese bacteria were not intended to be killed