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Table 2 Bodyweight, dose of infused bacteria, and in vivo blood bacterial counts

From: Mode of bacterial killing affects the inflammatory response and associated organ dysfunctions in a porcine E. coli intensive care sepsis model

Variable

Cefuroxime

Live E. coli

Heat

Cefuroxime + tobramycin

Bodyweight (kg)

26.0 ± 2.0

24.7 ± 1.4

26.6 ± 1.5

25.5 ± 2.7

Infused bacteria, total dose (log10 CFU)

8.78 ± 0.06

8.78 ± 0.07a

8.71 ± 0.05

8.74 ± 0.05

Infused bacteria, live bacterial dose (log10 CFU)

5.50 ± 0.40

8.78 ± 0.07

0.85 ± 1.70

2.39 ± 1.70

Blood bacterial count in vivo (log10 CFU × ml−1)

0 h

< 0.5

< 0.5

< 0.5

< 0.5

1 h

< 0.5

2.83 ± 0.38

< 0.5

< 0.5

2 h

< 0.5

3.18 ± 0.48

< 0.5

< 0.5

3 h

< 0.5

3.30 ± 0.53

< 0.5

< 0.5

4–6 h

< 0.5

< 0.5

< 0.5

< 0.5

  1. Mean ± SD; CFU colony-forming unit
  2. aThese bacteria were not intended to be killed