Table 2 Clinical characteristics, laboratory parameters and coagulation profiles among patients who experienced bleeding complications
Characteristic | n = 15 |
|---|---|
Age (years), median (IQR) | 60 (51–71) |
Sex, n (%) | |
 Male | 14 (93.3) |
 Female | 1 (6.7) |
Admission APACHE II score, median (IQR) | 14 (9–16) |
Bleeding complications, n (%) | 15 (8.0) |
 Gastrointestinal | 6 (3.2) |
 Intracranial | 5 (2.7) |
 Other (epistaxis (n = 1), Tracheostomy (n = 1), GU (n = 2)) | 4 (2.1) |
Severity of bleeding, n (%) | |
 Major | 9 (60) |
 Non-major | 6 (40) |
Anticoagulation, n (%) | |
 Prophylactic | 8 (53.3) |
 Therapeutic | 5 (33.3) |
 Data not available | 2 (13.4) |
Time interval between ICU admission and bleeding episode (days), median (IQR) | 15 (6–25) |
No. requiring red blood cell transfusion, n (%) | 7 (46.7) |
SOFA score at time of bleed, median (IQR) | 9 (5–12) |
Organ support requirement (n = 12), n |  |
 0–1 advanced organ support requirement | 6 |
 > 1 advanced organ support requirement | 6 |
Laboratory data at time of bleeding episode (n = 12) | |
 Platelet count (× 109/L), median (IQR) | 244 (163–325) |
 Prothrombin time (seconds), median (IQR) | 11.3 (10.6–11.8) |
 Activate partial thromboplastin time (seconds), median (IQR) | 27.2 (23.6–34.2) |
 Fibrinogen (g/L), median (IQR) | 4.8 (2.8–6.3) |
ICU length of stay (days), median (IQR) | 20 (10–35) |