Table 1 Differences in clinical characteristics at ICU admission between hypersecretive and normosecretive patients
All (n = 60) | Normosecretive (n = 30) | Hypersecretive (n = 30) | pvalue* | |
|---|---|---|---|---|
Age, median (IQR) | 69 (59–78) | 69 (61–76) | 67 (58–78) | 0.70 |
Gender (male) | 35 (58.33%) | 17 (56.7%) | 18 (60%) | 0.79 |
BMI, median (IQR) | 27.19 (24.22–29.39) | 26.79 (24.10–29.38) | 27.36 (24.22–29.40) | 0.62 |
Height, cm; median (IQR) | 170 (165–175) | 169 (165–175) | 170 (170–175) | 0.39 |
Comorbidities,n | ||||
Ischaemic heart disease | 6 (10.00%) | 4 (13.30%) | 2 (6.7%) | 0.67 |
Congestive heart failure | 12 (20.00%) | 7 (23.30%) | 5 (16.70%) | 0.52 |
Hypertension | 30 (50.00%) | 15 (50%) | 15 (50%) | 1.00 |
Cerebrovascular events | 12 (20.00%) | 6 (20.00%) | 6 (20.00%) | 1.00 |
Cognitive impairment | 2 (3.33%) | 1 (3.33%) | 1 (3.33%) | 1.00 |
COPD | 20 (33.33%) | 10 (33.33%) | 10 (33.33%) | 1.00 |
Diabetes mellitus | 17 (28.33%) | 8 (26.70%) | 9 (30.00%) | 0.77 |
Moderate to severe CKD | 4 (6.67%) | 1 (3.30%) | 3 (10.00%) | 0.61 |
Cause of admission,n | ||||
Respiratory | 23.00 (38.33%) | 11 (36.70%) | 12 (40.00%) | 0.96 |
Cardiovascular | 9.00 (15.00%) | 5 (16.70%) | 4 (13.30%) | 1.00 |
Neurologic | 19.00 (31.67) | 10 (33.30%) | 9 (30.00%) | 0.96 |
Trauma/burn/other | 9.00 (15.00%) | 4 (13.30%) | 5 (16.7%) | 1.00 |
APACHE-II median (IQR) | 17.50 (14.00–23.00) | 16.00 (12.00–24.00) | 19.00 (15.00–22.00) | 0.51 |
SOFA, median (IQR) | 7.50 (6.00–12.00) | 6.00 (4.5–11.25) | 8.5 (6.0–11.75) | 0.18 |
SAPS2, mean (SD) | 53.05 (18.73) | 53.47 (21.37) | 52.63 (16.02) | 0.86 |
Mode of ventilation (VC/PSV),n | 8/52 | 4/26 | 4/26 | 1.00 |