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Table 3 Primary and secondary outcome parameters according to ventilation mode (CV conventional ventilation, AV automated ventilation)

From: Automated vs. conventional ventilation in the ICU: a randomized controlled crossover trial comparing blood oxygen saturation during daily nursing procedures (I-NURSING)

Outcome parameters CV period
n = 265
AV period
n = 265
p
Primary outcome
 Time spent with SpO2 in the acceptable range—% of DNP duration* 43 ± 37 (38–47) 48 ± 37 (43–52) 0.03
Secondary outcome
 Patients with SpO2 in the acceptable range during DNP—n (%)* 123 (46%) 160 (60%) 0.001
 Patients with at least one episode of:
  SpO2 ≤ 85%**—n (%) 50 (19%) 30 (11%) 0.02
  SpO2 < 90%**—n (%) 92 (35%) 69 (26%) 0.03
 Time spent with:
  SpO2 ≤ 85%—% of DNP duration 3 ± 8 (2–4) 2 ± 6 (1–2) 0.03
  SpO2 < 90%—% of DNP duration 6 ± 11 (5–7) 5 ± 12 (3–6) 0.02
  FiO2 100%—% of DNP duration 6 ± 12 (4–7) 4 ± 10 (3–6) 0.09
 SpO2 mean—% 95 ± 3 (95–95) 95 ± 3 (95–95) 0.81
 SpO2 min—% 91 ± 6 (90–91) 91 ± 8 (90–92) 0.20
 SpO2 max—% 97 ± 2 (97–98) 97 ± 2 (97–98) 0.63
  1. Categorical variables are expressed as n (%) and continuous variables as mean ± standard deviation (95% confidence interval)
  2. DNP daily nursing procedure, SpO2 blood oxygen pulse saturation, FiO2 fraction of inspired oxygen, SpO2 mean mean SpO2 during DNP, SpO2 min minimal SpO2 recorded during DNP, SpO2 max maximal SpO2 recorded during DNP
  3. *SpO2 acceptable range was ≥ 90 and ≤ 95%
  4. **For more than 1 min