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Table 2 General, hemodynamic and ventilation parameters during daily nursing procedure (DNPs) according to ventilation mode (CV conventional ventilation, AV automated ventilation)

From: Automated vs. conventional ventilation in the ICU: a randomized controlled crossover trial comparing blood oxygen saturation during daily nursing procedures (I-NURSING)

Parameters CV period
n = 265
AV period
n = 265
p
DNP parameters
 DNPs duration—min 12 ± 6 (11–13) 12 ± 8 (11–13) 0.95
 Ramsay score 4 ± 2 (4–4) 4 ± 1 (4–4) 0.35
Oxygenation before DNPs
 SpO2—%* 96 ± 3 (95–96) 95 ± 3 (95–95) < 0.001
 SpO2/FiO2* 320 ± 79 (310–329) 317 ± 87 (306–327) 0.49
 PaO2/FiO2** 268 ± 95 (255–282) 266 ± 92 (253–280) 0.10
Hemodynamics during DNPs
 Heart rate—bpm † 98 ± 19 (95–100) 98 ± 20 (96–101) 0.32
 Mean arterial pressure—mmHg 89 ± 14 (87–90) 88 ± 15 (86–90) 0.56
Ventilation during DNPs
 Mode used in the CV period—n (%)
  Biphasic positive airway pressure 230 (87%)
  Pressure support ventilation 23 (9%)
  Volume controlled 12 (4%)
 Tidal volume—mL/kg of PBW 10 ± 3 (10–10) 10 ± 2 (10–10) 0.40
 Total RR—breath/min 28 ± 9 (27–29) 27 ± 8 (26–28) 0.79
 Spontaneous RR—breath/min 14 ± 11 (13–15) 22 ± 12 (21–24) < 0.001
 Passive ventilation—n (%)*** 35 (13%) 9 (3%) < 0.001
 Peak airway pressure—cmH2O 27 ± 6 (26–27) 25 ± 7 (24–26) < 0.001
 Mean airway pressure—cmH2O 15 ± 4 (14–15) 14 ± 4 (14–15) < 0.001
 PEEP—cmH2O 9 ± 3 (9–10) 9 ± 3 (9–10) 0.07
  1. Categorical variables are expressed as n (%) and continuous variables as mean ± standard deviation (95% confidence interval)
  2. PBW predicted body weight, RR respiratory rate, PetCO2 end-tidal CO2 partial pressure, PEEP positive end-expiratory pressure
  3. *Measured the minute before starting the DNP
  4. **Measured 5 min before starting the DNP
  5. ***Defined as no spontaneous breathing detected by the ventilator
  6. Mean of the overall parameters monitored every minute during the DNP