Table 1 Adjustment of unfractionated heparin dose during ECMO according to anti-Xa activity and body weight. 20,000 IU UFH + 44 cc NaCl 0.9%
Anti-Xa activity | Bolus | Variation | 55–64 kg | 65–74 kg | 75–84 kg | 85–94 kg | 95–104 kg | 105–114 kg | 115–124 kg |
|---|---|---|---|---|---|---|---|---|---|
< 0.2 | 26 U/kg | ↑96 U/kg/h | ↑0.6 cc/h | ↑0.7 cc/h | ↑0.8 cc/h | ↑0.9 cc/h | ↑1 cc/h | ↑1.1 cc/h | ↑1.2 cc/h |
0.20–0.29 | No | ↑48 U/kg/h | ↑0.3 cc/h | ↑0.3 cc/h | ↑0.4 cc/h | ↑0.4 cc/h | ↑0.5 cc/h | ↑0.6 cc/h | ↑0.7 cc/h |
0.30–0.70 | No |  |  |  |  |  |  |  |  |
0.71–0.80 | No | ↓24 U/kg/h | ↓0.1 cc/h | ↓0.1 cc/h | ↓0.2 cc/h | ↓0.2 cc/h | ↓0.2 cc/h | ↓0.3 cc/h | ↓0.3 cc/h |
0.81–0.99 | No | ↓48 U/kg/h | ↓0.3 cc/h | ↓0.3 cc/h | ↓0.4 cc/h | ↓0.4 cc/h | ↓0.5 cc/h | ↓0.6 cc/h | ↓0.7 cc/h |
> 1 | No | ↓96 U/kg/h | ↓0.6 cc/h | ↓0.7 cc/h | ↓0.8 cc/h | ↓0.9 cc/h | ↓1.0 cc/h | ↓1.1 cc/h | ↓1.2 cc/h |