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Table 2 Comparison of laboratory parameters before and after UC-MSC therapy

From: Administration of umbilical cord mesenchymal stem cells in patients with severe COVID-19 pneumonia

Characteristics Before UC-MSC therapy After UC-MSC therapy P value
White blood cell count, × 109/mL (normal range, 3.5–9.5) 6.72 ± 2.62 6.43 ± 1.72 0.346
Lymphocyte count, × 109/mL (normal range, 1.1–3.2) 1.09 (0.68–1.35) 1.43 (1.02–2.20) < 0.001
C-reactive protein, mg/L (normal range, < 10) 13.39 (1.30–38.86) 0.50 (0.50–6.40) 0.003
Procalcitonin, ng/mL (normal range, < 0.05) 0.07 (0.05–0.09) 0.04 (0.03–0.06) < 0.001
Interleukin-6, pg/mL (normal range, < 7) 13.78 (5.69–25.26) 4.86 (2.13–8.19) < .001
D-dimer, ng/mL (normal range, < 243) 495 (320–727) 288 (197–537) 0.010
PaO2/FiO2 242 (200–294) 332 (288–364) < 0.001
  1. UC-MSCs umbilical cord mesenchymal stem cells, PaO2/FiO2ratio ratio of the partial pressure of arterial oxygen to the percentage of inspired oxygen