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Table 2 Comparison of laboratory parameters before and after UC-MSC therapy

From: Administration of umbilical cord mesenchymal stem cells in patients with severe COVID-19 pneumonia

Characteristics

Before UC-MSC therapy

After UC-MSC therapy

P value

White blood cell count, × 109/mL (normal range, 3.5–9.5)

6.72 ± 2.62

6.43 ± 1.72

0.346

Lymphocyte count, × 109/mL (normal range, 1.1–3.2)

1.09 (0.68–1.35)

1.43 (1.02–2.20)

< 0.001

C-reactive protein, mg/L (normal range, < 10)

13.39 (1.30–38.86)

0.50 (0.50–6.40)

0.003

Procalcitonin, ng/mL (normal range, < 0.05)

0.07 (0.05–0.09)

0.04 (0.03–0.06)

< 0.001

Interleukin-6, pg/mL (normal range, < 7)

13.78 (5.69–25.26)

4.86 (2.13–8.19)

< .001

D-dimer, ng/mL (normal range, < 243)

495 (320–727)

288 (197–537)

0.010

PaO2/FiO2

242 (200–294)

332 (288–364)

< 0.001

  1. UC-MSCs umbilical cord mesenchymal stem cells, PaO2/FiO2ratio ratio of the partial pressure of arterial oxygen to the percentage of inspired oxygen