Table 3 Absence (% of cases) of claudin-5 and ZO-1 expression in different brain anatomical area and presence or absence of BBB damage
From: Brain tight junction protein expression in sepsis in an autopsy series
Area | All, N = 47 | BBB damage, N = 18 | No BBB damage, N = 29 | p |
|---|---|---|---|---|
Cerebrum | ||||
ZO1 | ||||
Endothelium | 1 (2.1%) | 1 (5.6%) | 0 (0%) | 0.383 |
Claudin-5 | ||||
Endothelium | 2 (4.3%) | 1 (5.6%) | 1 (3.5%) | > 0.9 |
Cerebellum | ||||
ZO1 | ||||
Endothelium | 0 (0%) | 0 (0%) | 0 (0%) | NA |
Claudin-5 | ||||
Endothelium | 0 (0%) | 0 (0%) | 0 (0%) | NA |