Towards a fasting-mimicking diet for critically ill patients: the pilot randomized crossover ICU-FM-1 study

Table 1 Baseline characteristics of participants

Baseline characteristic	Fasting–feeding N = 35	Feeding–fasting N = 35	Controls N = 23
Age—median [IQR]	63.2 [51.5–72.8]	67.7 [57.6–74.4]	69.2 [55.8–79.4]
Male gender—n (%)	18 (51.4)	18 (51.4)	10 (43.5)
BMI—median [IQR]	25.2 [23.3–31.6]	24.6 [21.7–27.1]	27.3 [24.3–29.4]
Admission to surgical ICU—n (%)	22 (62.9)	22 (62.9)	NA
Cardiac surgery—n (%)	7 (20.0)	6 (17.1)	NA
Emergency admission—n (%)	32 (91.4)	31 (88.6)	NA
Sepsis upon ICU admission—n (%)	19 (54.3)	20 (57.1)	NA
APACHE II—median [IQR]	33 [27–35]	31 [25–36]	NA
NRS score—median [IQR]	4 [3–5]	4 [4–5]	NA
Diabetes—n (%)	7 (20.0)	8 (22.9)	3 (13.0)
History of malignancy—n (%)	10 (28.6)	10 (28.6)	3 (13.0)
Pre-admission dialysis—n (%)	2 (5.7)	0 (0.0)	0 (0.0)
Study day—median [IQR]	8 [8–10]	8 [8–9]	NA
SOFA score on randomization day—median [IQR]	8 [6–10]	7 [6–11]	NA

Abbreviations: IQR interquartile range, BMI body mass index, ICU intensive care unit, APACHE Acute Physiology and Chronic Health Evaluation, NRS Nutritional Risk Screening, SOFA Sequential Organ Failure Assessment

ISSN: 1364-8535