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Table 3 Prescription of daily fluid balance target during CRRT and outcomes

From: Fluid removal associates with better outcomes in critically ill patients receiving continuous renal replacement therapy: a cohort study

 

Proportion of days when a daily FB target was set

0%

> 0 to < 50%

50 to < 80%

80 to < 100%

100%

n (%)

13 (2%)

27 (3%)

201 (25%)

266 (32%)

313 (38%)

Age, median [IQR]

58 [51–74]

65 [55–74]

66 [52–74]

63 [50–73]

67 [53–76]

SOFA score at CRRT initiation, mean (SD)

14.3 (5.1)

11.9 (4.7)

10.1 (4.0)

10.8 (3.5)

9.8 (3.6)

Maximum SOFA score during CRRT, mean (SD)

16.3 (4.5)

14.7 (4.4)

12.4 (4.0)

13.9 (3.0)

11.7 (3.7)

No FB nadir during CRRT, n (%)

12 (92%)

23 (81%)

74 (37%)

44 (17%)

70 (22%)

One or more fluid boluses received during CRRT, n (%)

11 (85%)

21 (78%)

151 (75%)

238 (89%)

202 (65%)

Blood transfusion received during CRRT, n (%)

10 (77%)

21 (78%)

134 (67%)

243 (91%)

214 (68%)

Any diuretics received during CRRT, n (%)

4 (31%)

9 (33%)

93 (46%)

152 (57%)

178 (57%)

Any noradrenaline received during RRT, n (%)

8 (62%)

19 (70%)

141 (70%)

231 (87%)

210 (37%)

Percentage of days when noradrenaline was given during CRRT, median [IQR]

100 [0–100]

100 [0–100]

50 [0–100]

42 [20–80]

42 [0–80]

Daily noradrenaline dose [μg], mean*

0

5 (39%)

8 (30%)

60 (30%)

35 (13%)

103 (33%)

1–4999

0

5 (19%)

18 (9%)

42 (16%)

37 (12%)

5000–9999

0

0

26 (13%)

33 (12%)

31 (10%)

10,000–49,999

2 (15%)

5 (19%)

71 (35%)

139 (52%)

105 (34%)

 50,000

6 (46%)

9 (33%)

26 (13%)

17 (6%)

37 (12%)

Days on CRRT, median [IQR]

2 [2–3]

3 [3–6]

4 [3–8]

14 [8–24]

5 [4–9]

ICU mortality, n (%)

12 (92%)

20 (74%)

74 (32%)

85 (32%)

73 (23%)

  1. Abbreviations: CRRT continuous renal replacement therapy, FB fluid balance, ICU intensive care unit, IQR interquartile range, SOFA Sequential Organ Failure Assessment, SD standard deviation
  2. *Mean daily dose across all days on RRT in mg