Table 2 Cumulative fluid balance in survivors and non-survivors
Parameters | ICU non-survivors (n = 264**) | ICU survivors (n = 556**) | p value | Hospital non-survivors (n = 331**) | Hospital survivors (n = 489**) | p value |
|---|---|---|---|---|---|---|
Cumulative FB on day of CRRT initiation | ||||||
Cum FB (ml) * | 2170 [739–5451] | 1581 [263–4254] | < 0.001 | 2184 [707–5323] | 1495 [238–404] | < 0.001 |
Cum FB (% BW)* | 2.9 [0.9–7.2] | 2.1 [0.3–5.7] | 0.001 | 2.9 [0.9–7.2] | 2.0 [0.3–5.4] | < 0.001 |
Cum FB ≤ 5% BW, n (%) | 167 (30) | 390 (70) | 0.034 | 211 (38) | 346 (62) | 0.032 |
Cum FB > 5% BW, n (%) | 90 (38) | 149 (62) | 110 (46) | 129 (54) | ||
Cum FB ≤ 10% BW, n (%) | 222 (31) | 485 (69) | 0.132 | 276 (39) | 431 (61) | 0.037 |
Cum FB > 10% BW, n (%) | 35 (39) | 54 (61) | 45 (51) | 44 (49) | ||
Cum FB ≤ median FB (1772 ml), n (%) | 112 (27) | 298 (73) | 0.003 | 142 (35) | 268 (65) | 0.001 |
Cum FB > median FB (1772 ml), n (%) | 152 (37) | 258 (63) | 189 (46) | 221 (54) | ||
Cumulative FB at nadir during CRRT | ||||||
Cum FB (ml) * | 1115 [− 656 to 3493] | − 275 [− 4401 to 1714] | < 0.001 | 990 [− 1078 to 3239] | −361 [− 4729 to –1709] | < 0.001 |
Cum FB (% BW)* | 1.6 [− 0.8 to 4.7] | − 0.3 [− 4.9 to –2.5] | < 0.001 | 1.2 [− 1.6 to 4.0] | −0.6 [− 5.5 to –2.1] | < 0.001 |
Delta cumulative FB (i.e. maximum change in cumulative FB between initiation of CRRT and nadir) | ||||||
Delta FB (ml) * | 541 [0–3461] | 2479 [183–6242] | < 0.001 | 882 [0–3651] | 2688 [286–6512] | < 0.001 |
Delta FB (% BW)* | 0.9 [0–4.7] | 3.1 [0.3–7.7] | < 0.001 | 1.4 [0–5.0] | 3.3 [0.3–8.0] | < 0.001 |
Time to nadir of cumulative FB*** | ||||||
1 to 3 days | 54 (26) | 152 (74) | 0.746 | 73 (35) | 133 (65) | 0.577 |
> 3 days | 98 (25) | 294 (75) | 130 (33) | 262 (67) | ||