Table 3 Estimates of the effect of covariates on 28- and 90-day mortality as evaluated in the eight Cox proportional hazards models
Variable | Mortality at 28 days | Mortality at 90 days | ||||||
|---|---|---|---|---|---|---|---|---|
Model | Incident delirium | Days of delirium | Days of coma | Days of delirium or coma | Incident delirium | Days of delirium | Days of coma | Days of delirium or coma |
Age | 1.04 (1.03–1.06) | 1.04 (1.03–1.06) | 1.05 (1.03–1.06) | 1.04 (1.03–1.05) | 1.04 (1.03–1.05) | 1.04 (1.03–1.05) | 1.04 (1.03–1.05) | 1.04 (1.03–1.05) |
APACHE II score | 1.07 (1.06–1.09) | 1.07 (1.06–1.09) | 1.07 (1.05–1.09) | 1.07 (1.06–1.09) | 1.07 (1.05–1.08) | 1.07 (1.05–1.08) | 1.06 (1.05–1.08) | 1.06 (1.05–1.08) |
Sepsis present | 1.89 (1.46–2.43) | 1.87 (1.45–2.42) | 1.73 (1.33–2.24) | 1.87 (1.45–2.42) | 1.86 (1.48–2.33) | 1.85 (1.47–2.33) | 1.72 (1.36–2.17) | 1.78 (1.41–2.25) |
Mechanical ventilation use | 2.81 (1.88–4.19) | 2.77 (1.86–4.13) | 2.24 (1.50–3.36) | 2.49 (1.66–3.72) | 2.16 (1.54–3.05) | 2.14 (1.53–3.00) | 1.83 (1.30–2.58) | 1.95 (1.38–2.74) |
ICU Length of Stay | 0.97 (0.95–0.99) | 0.97 (0.96–0.99) | 0.92 (0.90–0.95) | 0.95 (0.92–0.97) | 1.00 (0.98–1.01) | 1.00 (0.98–1.01) | 0.97 (0.95–0.99) | 0.98 (0.97–1.00) |
Study Arm | ||||||||
 Haloperidol 2 mg | 1.08 (0.78–1.49) | 1.06 (0.76–1.47) | 1.20 (0.87–1.66) | 1.29 (0.93–1.78) | 1.17 (0.88–1.56) | 1.18 (0.89–1.58) | 1.31 (0.98–1.74) | 0.97 (0.76–1.25) |
 Haloperidol 1 mg | 1.18 (0.84–1.66) | 1.16 (0.83–1.64) | 1.12 (0.79–1.58) | 1.21 (0.86–1.71) | 1.15 (0.84–1.57) | 1.15 (0.84–1.57) | 1.16 (0.85–1.60) | 0.99 (0.73–1.35) |