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Table 1 Subject characteristics

From: Alveolar MMP28 is associated with clinical outcomes and measures of lung injury in acute respiratory distress syndrome

Characteristic

ARDS cohort

(n = 76)

Demographic

 Age (mean ± SD)

50 ± 16

 Sex (M/F)

45/31

Comorbidities

 Diabetes

16 (22%)

 Cirrhosis

5 (7%)

 Chronic renal insufficiency

2 (3%)

ARDS risk factor*, n (%)

 Sepsis

48 (64%)

 Pneumonia

31 (41%)

 Trauma

27 (37%)

 Other

8 (11%)

Physiologic

 P/F Ratio (median, IQR)

156, (121–205)

 APACHE II (mean ± SD)

22 ± 7

Outcome

 VFDs (median, IQR)

14, (0–21)

 Mortality (28-day) (n, %)

11, 20%

  1. *ARDS risk factors are not mutually exclusive; APACHE Acute Physiology, Age, Chronic Health Evaluation, ARDS acute respiratory distress syndrome, IQR interquartile range, P/F ratio PaO2/FiO2 ratio, SD standard deviation, VFDs ventilator-free days—defined as the number of days a subject is alive and free from mechanical ventilation between day 1 and day 28 after enrollment. If a subject died before day 28, they were considered to have VFDs = 0