Fig. 1

Alveolar MMP28 is associated with clinical outcomes in subjects with acute respiratory distress syndrome (ARDS). a AM-specific relative gene expression of MMP28 was higher in subjects with worse ventilator-free days (VFDs) (VFDs < 14) vs. better VFDs (VFDs ≥ 14) (p = 0.048, unpaired t test). Subjects were divided by the median VFDs (VFD = 14). Shown are the individual values, mean, and standard deviation. b AM-specific relative gene expression of MMP28 was higher in subjects with a P/F ratio < 150 vs. P/F ratio ≥ 150 (p = 0.03, unpaired t test). Shown are the individual values, mean, and standard deviation. C) BALF MMP28 concentrations were not different in subjects with worse VFDs (VFDs < 14) vs. better VFDs (VFDs ≥14) (p = 0.55, Wilcoxon rank test). Shown are the individual values, median, and interquartile range. d BALF MMP28 concentrations were higher in subjects with a P/F ratio < 150 vs. P/F ratio ≥ 150 (p < 0.01, Wilcoxon rank test). Shown are the individual values, median, and interquartile range. e BALF MMP28 concentrations were higher in subjects with % PMNs > 50% vs. subjects with % PMNs ≤50% (p = 0.03, Wilcoxon rank test). Shown are the individual values, median, and interquartile range. f BALF MMP28 concentrations were higher in subjects with higher alveolar total protein vs. subjects with lower alveolar total protein (p < 0.01, Wilcoxon rank test). Subjects were divided by the median alveolar total protein concentration (306.5 μg/mL). Shown are the individual values, median, and interquartile range