Fig. 2From: Impact of acyclovir use on survival of patients with ventilator-associated pneumonia and high load herpes simplex virus replicationa–c Kaplan-Meier analysis of intensive care unit survival after starting antiviral treatment or after HSV detection: day 0 (d0) was defined as the date of first detection of significant HSV-1/2 replication in untreated patients or as the date of acyclovir treatment start for patients receiving. + = censored. The p values were calculated using a log-rank test. a Entire cohort. b Subgroup with low viral load (103–105 HSV copies/mL). c Subgroup with high viral load (> 105 HSV copies/mL)Back to article page