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Table 2 Baseline laboratory parameters of study groups

From: 0.9% saline versus Plasma-Lyte as initial fluid in children with diabetic ketoacidosis (SPinK trial): a double-blind randomized controlled trial

ParameterPlasma-Lyte -A(n = 34)0.9% saline (n = 32)P value
Blood glucose at 0 h (mg/dl)488 (435, 618)430 (367, 477)0.003
Blood glucose at 1 h (mg/dl)470 (389, 579)393 (326, 456)0.004
Blood Ketones (mmol/L)5.5 (5.0, 6.6)5.3 (4.6, 6.3)0.079
pH6.98 (6.90, 7.16)6.99 (6.90, 7.15)0.974
Bicarbonate (mmol/L)6.9 (5.8, 9.5)6.8 (5.4, 8.6)0.464
pCO2 (mm Hg)20.8 (16.0, 27.6)19.6 (15.3, 24.8)0.379
Base deficit (mmol/L)22.1 (18.5, 25.5)23.1 (18.4, 25.9)0.517
Electrolytes
 Sodium (mmol/L)138.0 (131.5, 143.0)137.5 (134.2, 141.5)0.837
 Corrected sodium (mmol/L)143.0 (139, 148.3)143 (139, 146)0.639
 Chloride (mmol/L)112.5 (103.7, 117.7)111 (105.2, 117.7)0.908
 Potassium (mmol/L)4.1 (3.4, 4.8)3.8 (3.2, 4.4)0.264
 Phosphate (mg/dl)2.9 (1.75, 3.2)2.7 (2.52, 3.5)0.393
 Urea (mg/dl)31.5 (24.0, 52.0)32.5 (23.3, 54.8)0.923
 Creatinine (mg/dl)0.8 (0.6, 1.07)0.68 (0.5, 1.0)0.21
 Anion gap (mmol/L)19.8 (16.1, 22.9)18.9 (15.8, 22.3)0.419
 Osmolality (mmol/kg)300 (293, 308)298 (292, 307)0.369
 Lactate (mmol/L)2 (1.3, 2.5)2 (1.4, 2.3)0.903
 Urinary NGAL at 0 h (ng/ml)73.61 (41.7, 95.6)82.46 (36.1, 92.2)0.9
Others
 Hemoglobin (g/dl)11.9 (10.2, 12.9)11.0 (10.1, 12.3)0.193
 Total leukocyte count (per cu.mm)13,075 (10,100, 23,775)13,900 (8895, 21,802)0.758
 HbA1C (%)12.2 (11.25, 14.0)12.7 (9.28, 12.75)0.842
 C peptide (ng/ml)0.16 (0.05, 0.39)0.33 (0.20, 0.69)0.016
 Vitamin D (ng/ml)10.48 (4.89, 14.4)10.27 (3.34, 17.8)0.881
 PTH (pg/ml)14.55 (8.31, 25.69)21.6 (13.22, 28.23)0.275
  1. Data expressed as median (IQR), p<0.05 was considered significant
  2. SI conversion factors: To convert glucose to mmol/L, multiply values by 0.055. To convert creatinine to micromol/L, multiply values by 88.4. To convert phosphate to mmol/L, multiply values by 0.323.
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