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Table 2 Baseline laboratory parameters of study groups

From: 0.9% saline versus Plasma-Lyte as initial fluid in children with diabetic ketoacidosis (SPinK trial): a double-blind randomized controlled trial

Parameter

Plasma-Lyte -A(n = 34)

0.9% saline (n = 32)

P value

Blood glucose at 0 h (mg/dl)

488 (435, 618)

430 (367, 477)

0.003

Blood glucose at 1 h (mg/dl)

470 (389, 579)

393 (326, 456)

0.004

Blood Ketones (mmol/L)

5.5 (5.0, 6.6)

5.3 (4.6, 6.3)

0.079

pH

6.98 (6.90, 7.16)

6.99 (6.90, 7.15)

0.974

Bicarbonate (mmol/L)

6.9 (5.8, 9.5)

6.8 (5.4, 8.6)

0.464

pCO2 (mm Hg)

20.8 (16.0, 27.6)

19.6 (15.3, 24.8)

0.379

Base deficit (mmol/L)

22.1 (18.5, 25.5)

23.1 (18.4, 25.9)

0.517

Electrolytes

 Sodium (mmol/L)

138.0 (131.5, 143.0)

137.5 (134.2, 141.5)

0.837

 Corrected sodium (mmol/L)

143.0 (139, 148.3)

143 (139, 146)

0.639

 Chloride (mmol/L)

112.5 (103.7, 117.7)

111 (105.2, 117.7)

0.908

 Potassium (mmol/L)

4.1 (3.4, 4.8)

3.8 (3.2, 4.4)

0.264

 Phosphate (mg/dl)

2.9 (1.75, 3.2)

2.7 (2.52, 3.5)

0.393

 Urea (mg/dl)

31.5 (24.0, 52.0)

32.5 (23.3, 54.8)

0.923

 Creatinine (mg/dl)

0.8 (0.6, 1.07)

0.68 (0.5, 1.0)

0.21

 Anion gap (mmol/L)

19.8 (16.1, 22.9)

18.9 (15.8, 22.3)

0.419

 Osmolality (mmol/kg)

300 (293, 308)

298 (292, 307)

0.369

 Lactate (mmol/L)

2 (1.3, 2.5)

2 (1.4, 2.3)

0.903

 Urinary NGAL at 0 h (ng/ml)

73.61 (41.7, 95.6)

82.46 (36.1, 92.2)

0.9

Others

 Hemoglobin (g/dl)

11.9 (10.2, 12.9)

11.0 (10.1, 12.3)

0.193

 Total leukocyte count (per cu.mm)

13,075 (10,100, 23,775)

13,900 (8895, 21,802)

0.758

 HbA1C (%)

12.2 (11.25, 14.0)

12.7 (9.28, 12.75)

0.842

 C peptide (ng/ml)

0.16 (0.05, 0.39)

0.33 (0.20, 0.69)

0.016

 Vitamin D (ng/ml)

10.48 (4.89, 14.4)

10.27 (3.34, 17.8)

0.881

 PTH (pg/ml)

14.55 (8.31, 25.69)

21.6 (13.22, 28.23)

0.275

  1. Data expressed as median (IQR), p<0.05 was considered significant
  2. SI conversion factors: To convert glucose to mmol/L, multiply values by 0.055. To convert creatinine to micromol/L, multiply values by 88.4. To convert phosphate to mmol/L, multiply values by 0.323.