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Table 1 Clinical and laboratory variables with follow-up for 1 week

From: A longitudinal study highlights shared aspects of the transcriptomic response to cardiogenic and septic shock

Clinical variable

Shock

T1

T2

T3

p value

Heart rate, bpm

CS

87 (9)

90 (15)

92 (23)

0.69532

SS

91 (22)

81 (13)

88 (22)

 

Systolic blood pressure, mmHg

CS

84 (11)

105 (24)

113 (34)

0.31639

SS

83 (11)

97 (16)

110 (17)

 

Diastolic blood pressure, mmHg

CS

51 (7)

52 (9)

63 (17)

0.01147

SS

45 (4)

49 (5)

53 (12)

 

Mean arterial pressure, mmHg

CS

61 (6)

69 (14)

79 (21)

0.04505

SS

57 (5)

64 (7)

72 (12)

 

Respiratory rate, rpm

CS

21 (5)

26 (7)

27 (3)

0.82505

SS

25 (8)

25 (6)

27 (8)

 

PaO2, mmHg

CS

92 (44)

79 (15)

77 (12)

0.17879

SS

85 (17)

76 (18)

70 (11)

 

PaCO2, mmHg

CS

35.0 (13.7)

39.3 (6.5)

38.8 (5.6)

0.10633

SS

44.1 (13.0)

40.3 (8.5)

38.5 (6.9)

 

SvcO2%

CS

64 (11)

67 (5)

86 (7)

0.49098

SS

73 (6)

69 (8)

61 (17)

 

FiO2

CS

0.59 (0.30)

0.35 (0.08)

0.33 (0.08)

0.87275

SS

0.52 (0.20)

0.34 (0.10)

0.33 (0.08)

 

PaO2/FiO2

CS

189 (109)

239 (70)

250 (73)

0.51411

SS

194 (103)

245 (89)

229 (64)

 

Temperature, °C

CS

36.7 (1.5)

37.3 (0.8)

36.7 (1.0)

0.01178

SS

37.6 (0.9)

37.5 (0.9)

37.5 (1.3)

 

Urine output, mL/day

CS

1492 (851)

2184 (926)

1963 (1323)

0.18808

SS

1494 (831)

2272 (1057)

2591 (1219)

 

Fluid balance, mL

CS

1427 (1417)

197 (1104)

− 17 (1267)

0.59677

SS

2591 (1958)

411 (1529)

− 815 (1358)

 

HCO3, mmol/L

CS

18.1 (3.9)

26.0 (3.9)

27.6 (3.6)

0.57272

SS

19.8 (3.9)

25.1 (4.8)

27.0 (5.0)

 

Norepinephrine, μg/(kg min)

CS

0.23 (0.2)

0.20 (0.22)

0.16 (0.13)

0.58250

SS

0.35 (0.29)

0.23 (0.34)

0.05 (0.02)

 

Bilirubin, mg/dL

CS

1.1 (0.6)

0.9 (0.4)

0.8 (0.6)

0.56664

SS

1.6 (1.8)

1.2 (1.4)

1.0 (1.2)

 

Glycemia, mg/dL

CS

218.2 (73.6)

146.9 (25.1)

140.9 (54.4)

0.37518

SS

183.9 (84.8)

142.8 (37.9)

129.8 (34.3)

 

Prothrombin time INR

CS

1.5 (0.8)

1.2 (0.5)

1.1 (0.1)

0.09433

SS

1.3 (0.3)

1.1 (0.2)

1.1 (0.2)

 

Fibrinogen, g/L

CS

4.11 (1.46)

4.34 (2.33)

7.15 (1.68)

0.02844

SS

5.32 (2.14)

6.35 (2.13)

6.81 (1.53)

 

CRP value, mg/L

CS

62.8 (49.3)

149.7 (74.8)

75.5 (39.2)

0.00001

SS

248.5 (140.6)

248.3 (112.5)

120.4 (71.0)

 

Creatinine, mg/dL

CS

1.4 (0.5)

1.3 (0.6)

1.0 (0.4)

0.61095

SS

1.9 (1.4)

1.4 (1.1)

1.1 (0.7)

 

Lactate levels, mmol/L

CS

4.9 (3.6)

1.2 (0.4)

1.2 (0.5)

0.84012

SS

4.3 (2.4)

1.7 (0.8)

1.2 (0.5)

 

SOFA

CS

11.0 (2.5)

7.5 (2.8)

5.2 (3.0)

0.36026

SS

12.1 (2.0)

8.8 (3.0)

5.5 (3.3)

 

Glasgow Coma Scale

CS

6 (4)

10 (3)

13 (3)

0.36746

SS

5 (4)

9 (3)

11 (3)

 

Platelets, 103/mm3

CS

260 (85)

208 (80)

295 (138)

0.16299

SS

205 (103)

176 (84)

235 (107)

 

Hematocrit %

CS

39.2 (4.0)

34.9 (4.9)

35.2 (4.4)

0.00360

SS

34.6 (5.0)

30.2 (5.2)

31.4 (4.4)

 

Leukocytes total, 103/mm3

CS

15.92 (5.36)

12.09 (4.20)

10.83 (2.93)

0.90718

SS

16.19 (13.94)

14.55 (7.67)

13.66 (5.36)

 

White blood cells, 109/L

CS

15.29 (6.00)

12.2 (4.61)

11.29 (2.95)

0.98992

SS

15.96 (14.22)

14.49 (7.95)

13.98 (5.59)

 

Lymphocytes, 109/L

CS

1.41 (0.70)

1.37 (0.65)

1.54 (0.67)

0.00007

SS

0.70 (0.60)

0.80 (0.54)

0.90 (0.47)

 

Neutrophils, 109/L

CS

10.75 (6.27)

10.50 (5.95)

7.60 (1.38)

0.10346

SS

14.49 (7.22)

11.32 (2.25)

12.14 (2.75)

 
  1. Clinical and laboratory characteristics of the patients divided by cardiogenic shock (CS) and septic shock (SS). Data are presented as mean (SD). p values were calculated with ANOVA and describe the significance of the difference between the variables in cardiogenic shock and septic shock over the three time points