Fig. 1

Flow diagram for inclusion and exclusion of eligible patients. Exclusion criteria were trauma following or combined with severe circulatory failure (cardiac arrest/cerebral hemorrhage), earlier TBI or CVA without full recovery, progressive brain illness (tumor, neurodegenerative disease), or limited life expectancy (< 6 months) prior to TBI. Besides, patients were not included because of practical reasons, for example, if the research team was not aware of the admission of a patient