Total (n = 116) | Non-AGI (n = 80) | AGI (n = 36) | t/Z/χ | p value | |
---|---|---|---|---|---|
Age (year) | 53.4 ± 20.6 | 53.9 ± 21.6 | 52.2 ± 18.5 | 0.41a | 0.68 |
Male/female, n (%) | 62/54 | 42/38 | 20/16 | 0.09c | 0.76 |
BMI (kg/m2) | 22.3 ± 3.9 | 22.1 ± 3.9 | 22.5 ± 4.0 | 0.49a | 0.63 |
Cause of ICU admission | |||||
Major trauma, n (%) | 59 (50.9) | 43 (53.8) | 16 (44.4) | 0.86c | 0.35 |
Complications after surgery, n (%) | 45 (38.8) | 30 (37.5) | 15 (41.7) | 0.18c | 0.67 |
Others, n (%) | 12 (10.3) | 7 (8.8) | 5 (13.9) | 0.71c | 0.40 |
Serum lactate at onset (mmol/L) | 2.4 ± 1.0 | 2.3 ± 1.0 | 2.5 ± 0.9 | 1.21a | 0.23 |
APACHE II on ICU admission | 15.0 [11.0–17.0] | 15.0 [11.0–17.0] | 14.5 [13.0–18.0] | 1.83b | 0.78 |
SOFA score on ICU admission | 10.0 [8.0–13.0] | 9.5 [8.0–13.0] | 10.0 [9.3–13.0] | 5.14b | 0.48 |
Mechanical ventilation, n (%) | 62 (53.5) | 36 (45.0) | 26 (72.2) | 7.40c | 0.007 |
PaO2/FiO2 (mmHg) | 206.5 ± 21.5 | 209.8 ± 20.7 | 199.1 ± 21.6 | 2.54a | 0.01 |
Platelet count (× 109/L) | 133.7 ± 19.7 | 137.11 ± 19.7 | 126.11 ± 17.7 | 2.87a | 0.005 |
Total bilirubin (mmol/L) | 70.1 ± 32.8 | 54.1 ± 22.7 | 105.8 ± 22.0 | 11.46a | < 0.001 |
MAP (mmHg) | 75.0 ± 6.2 | 75.2 ± 5.6 | 74.3 ± 7.4 | 0.76a | 0.45 |
Vasopressor support, n (%) | 59 (50.9) | 35 (43.8) | 24 (66.7) | 5.22c | 0.02 |
Norepinephrine, n (%) | 59 (50.9) | 35 (43.8) | 24 (66.7) | 5.22c | 0.02 |
Epinephrine, n (%) | 7 (6.0) | 2 (2.5) | 5 (13.9) | 5.68c | 0.02 |
Dobutamine, n (%) | 3 (2.6) | 0 (0) | 3 (8.3) | 6.84c | 0.009 |
Norepinephrine dose (μg/kg/min) | 0.06 [0.03–0.15] | 0.04 [0.03–0.06] | 0.15 [0.09–0.24] | 5.22b | < 0.001 |
At least two drugs, n (%) | 9 (7.8) | 2 (2.5) | 7 (19.4) | 9.96c | 0.002 |
Serum creatinine (μmol/L) | 94.0 [61.5–131.8] | 80.0 [50.5–107.3] | 162.0 [108.5–200.8] | 18.64b | < 0.001 |
Renal replacement therapy, n (%) | 34 (29.3) | 19 (23.8) | 15 (41.7) | 3.85c | 0.05 |
Intra-abdominal pressure (mmHg) | 10.6 ± 6.3 | 8.4 ± 5.5 | 15.5 ± 5.3 | 6.57a | < 0.001 |
Abdominal perfusion pressure (mmHg) | 64.3 ± 8.3 | 66.9 ± 7.8 | 58.8 ± 6.6 | 5.41a | < 0.001 |
Intra-abdominal hypertension, n (%) | 78 (67.2) | 43 (53.8) | 35 (97.2) | 21.30c | < 0.001 |
Feeding intolerance, n (%) | 41 (35.3) | 5 (6.3) | 36 (100) | 95.49c | < 0.001 |
Duration of mechanical ventilation (days) | 3.0 [0.0–12.8] | 1.0 [0–7.0] | 12.0 [0–14.8] | 4.48b | < 0.001 |
AGIUS score | 2.0 [1.0–3.0] | 2.0 [1.0–3.0] | 4.0 [3.0–4.0] | 5.85b | < 0.001 |
GUTS score | 3.0 [2.0–3.0] | 3.0 [2.0–3.0] | 3.0 [3.0–3.0] | 4.60b | < 0.001 |
Length of ICU stay (days) | 9.5 [6.0–18.0] | 8.0 [5.0–14.5] | 17.0 [8.8–21.0] | 3.38b | 0.001 |
Length of hospital stay (days) | 17.0 [11.0–23] | 14.0 [10.0–20.8] | 21.0 [19.0–25.8] | 3.75b | < 0.001 |
28-day mortality, n (%) | 42 (36.2) | 14 (17.5) | 28 (77.8) | 39.06c | < 0.001 |
ICU mortality, n (%) | 37 (31.9) | 12 (15.0) | 25 (69.4) | 38.21c | < 0.001 |
Hospital mortality, n (%) | 41 (35.3) | 14 (17.5) | 27 (75) | 35.92c | < 0.001 |