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Table 2 Odds of hospital mortality from multivariable logistic regression

From: Association between hospital mortality and inspiratory airway pressures in mechanically ventilated patients without acute respiratory distress syndrome: a prospective cohort study

 

Non-ARDS

ARDS

ORa

95% CI

p value

ORa

95% CI

p value

Driving pressure (per 7 cm H2O)b

1.36

1.14–1.62

< 0.001

1.63

1.22–2.16

< 0.001

Plateau pressure (per 8 cm H2O)b

1.42

1.17–1.73

< 0.001

1.74

1.26–2.41

< 0.001

Age (per 5 years)

1.05

0.98–1.11

0.125

1.09

0.99–1.20

0.07

PEEP (per 1 cm H2O)

1.05

0.98–1.11

0.16

1.12

1.07–1.17

< 0.001

APACHE II (per 1 point)

1.08

1.04–1.11

< 0.001

1.08

1.04–1.12

< 0.001

Vasopressor use

1.52

1.06–2.16

0.02

1.02

0.56–1.85

0.94

Sepsis

1.12

0.77–1.62

0.56

1.03

0.62–1.69

0.90

  1. Abbreviations: ARDS acute respiratory distress syndrome, APACHE Acute Physiologic and Chronic Health Evaluation, PEEP positive end-expiratory pressure, OR odds ratio
  2. Estimates for covariates are derived from the driving pressure model. The plateau pressure model included the same covariates as the driving pressure model
  3. aOdds ratio adjusted for age, sex, PEEP, APACHE II, vasopressor use, sepsis, hospital volume, and ICU category
  4. bOdds ratios for driving pressure and plateau pressure are scaled to IQRs
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Critical Care

ISSN: 1364-8535