Table 1 Patient characteristics
Patient characteristic | Primary cohort (n = 16) | External validation cohort (n = 12) |
|---|---|---|
N measurements in cohort | 52 | 46 |
N measurements per patienta | 3 (2–5) | 3 (1–7) |
Age (years) (mean, SD) | 63 (10) | 60 (57–73) |
Sex (n, % female) | 7 (44%) | 10 (83%) |
Cause of respiratory failure (n, %) | ||
 Pneumonia | 10 (62%) | 10 (83%) |
 Non-pulmonary sepsis | 2 (13%) | 0 (0%) |
 Cardiogenic shock | 0 (0%) | 2 (17%) |
 Intracranial hemorrhage | 3 (19%) | 0 (0%) |
 Ischemic stroke | 1 (6%) | 0 (0%) |
Sedation-Agitation Scale scoreb | 2 (2–3) | Not reported |
Baseline nadir PaO2/FiO2 (mm Hg) | 148 (105–173) | Not reported |
Mode of ventilation (n days, %) | ||
 Volume assist-control | 1 (2%) | – |
 Pressure assist-control | 9 (17%) | – |
 Pressure support | 39 (75%) | – |
 Not recorded | 3 (6%) | – |
 Neurally adjusted ventilatory assist | 0 (0%) | 12 (100%) |
ΔPaw (cm H2O)b | 5 (3–7) | 10 (9–17) |
Pmus (cm H2O)b | 16 (12–22) | 7 (5–9) |
ΔPL (cm H2O)b | 18 (14–23) | 18 (14–22) |