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Table 3 Results of multivariable analysis showing the adjusted hazard ratio associated with the 180-day and 365-day mortality of each variable

From: Impact of post-sepsis cardiovascular complications on mortality in sepsis survivors: a population-based study

Characteristics

180-day mortality, HR (95% CI)

P value

365-day mortality, HR (95% CI)

P value

Post-sepsis MI/stroke

2.02 (1.65, 2.47)

< .0001

2.02 (1.65, 2.47)

< .0001

Demographics

 Male sex

1.38 (1.27, 1.51)

< .0001

1.38 (1.27, 1.51)

< .0001

 Age

1.03 (1.02, 1.03)

< .0001

1.03 (1.02, 1.03)

< .0001

Urbanization level, %

 Level 1: urban area

1.70 (1.42, 2.03)

< .0001

1.69 (1.46, 1.95)

< .0001

 Level 2: metro area

1.40 (1.16, 1.69)

0.0005

1.45 (1.25, 1.69)

< .0001

 Level 3: suburban area

1.09 (0.91, 1.32)

0.3524

1.10 (0.94, 1.27)

0.2392

 Level 4: countryside area

Reference

–

Reference

–

Insurance premium level, % (New Taiwan dollars)

 Dependent

Reference

–

Reference

–

 No/poverty income level ($1–$19,999)

1.06 (0.94, 1.2)

0.3171

1.06 (0.94, 1.2)

0.3171

 Middle income level ($20,000–$39,999)

1.25 (1.1, 1.44)

0.001

1.25 (1.1, 1.44)

0.001

 High income level (≥ $40,000)

0.84 (0.68, 1.04)

0.1034

0.84 (0.68, 1.04)

0.1034

Preadmission comorbidity, %

 Myocardial infarction

1.03 (0.83, 1.28)

0.7758

1.03 (0.83, 1.28)

0.7758

 Congestive heart failure

1.16 (1.04, 1.29)

0.0069

1.16 (1.04, 1.29)

0.0069

 Peripheral vascular disease

0.90 (0.74, 1.1)

0.319

0.90 (0.74, 1.10)

0.319

 Cerebrovascular disease

1.16 (1.06, 1.28)

0.0021

1.16 (1.06, 1.28)

0.0021

 Dementia

1.47 (1.31, 1.65)

< .0001

1.47 (1.31, 1.65)

< .0001

 Chronic pulmonary disease

1.11 (1.02, 1.21)

0.022

1.11 (1.02, 1.21)

0.022

 Rheumatologic disease

1.27 (0.91, 1.78)

0.1602

1.27 (0.91, 1.78)

0.1602

 Peptic ulcer disease

0.96 (0.88, 1.06)

0.4459

0.96 (0.88, 1.06)

0.4459

 Mild liver disease

1.07 (0.95, 1.20)

0.2567

1.07 (0.95, 1.20)

0.2567

 Diabetes without chronic complications

1.09 (0.99, 1.20)

0.0987

1.09 (0.99, 1.20)

0.0987

 Diabetes with chronic complications

0.98 (0.85, 1.13)

0.7508

0.98 (0.85, 1.13)

0.7508

 Hemiplegia or paraplegia

1.56 (0.44, 5.47)

0.4913

1.56 (0.44, 5.47)

0.4913

 Renal disease

1.15 (1.02, 1.29)

0.0184

1.15 (1.02, 1.29)

0.0184

 Any malignancy, including leukemia and lymphoma

1.40 (1.25, 1.57)

< .0001

1.40 (1.25, 1.57)

< .0001

 Moderate or severe liver disease

1.72 (1.40, 2.10)

< .0001

1.72 (1.40, 2.10)

< .0001

 Metastatic solid tumor

1.19 (0.99, 1.44)

0.0717

1.19 (0.99, 1.44)

0.0717

 AIDS/HIV

2.05 (0.66, 6.39)

0.2172

2.05 (0.66, 6.39)

0.2172

 Alcohol/drug use

1.08 (0.83, 1.42)

0.5569

1.08 (0.83, 1.42)

0.5569

 Psychiatric disorder

0.96 (0.86, 1.07)

0.4139

0.96 (0.86, 1.07)

0.4139

 Neurologic disorder

1.03 (0.90, 1.18)

0.6724

1.03 (0.90, 1.18)

0.6724

 Obesity

0.75 (0.28, 2.00)

0.567

0.75 (0.28, 2.00)

0.567

 Bed-ridden status

0.76 (0.22, 2.66)

0.6717

0.76 (0.22, 2.66)

0.6717

 Solid organ transplantation such as renal or heart transplantation

1.26 (0.4, 3.92)

0.6922

1.26 (0.40, 3.92)

0.6922

Healthcare service utilization, %

 Number of OPD visits

1.00 (1.00, 1.00)

0.9105

1.00 (1.00, 1.00)

0.9105

 Number of emergency department visits

1.02 (1.01, 1.04)

0.0002

1.02 (1.01, 1.04)

0.0002

 Number of hospital admissions

1.08 (1.06, 1.10)

< .0001

1.08 (1.06, 1.10)

< .0001

  1. Summary of the variables associated with 180-day mortality and 365-day mortality using the Cox regression model
  2. MI myocardial infarction, AIDS/HIV acquired immune deficiency syndrome/human immunodeficiency virus, OPD outpatient department, HR hazard ratio