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Table 3 Results of multivariable analysis showing the adjusted hazard ratio associated with the 180-day and 365-day mortality of each variable

From: Impact of post-sepsis cardiovascular complications on mortality in sepsis survivors: a population-based study

Characteristics 180-day mortality, HR (95% CI) P value 365-day mortality, HR (95% CI) P value
Post-sepsis MI/stroke 2.02 (1.65, 2.47) < .0001 2.02 (1.65, 2.47) < .0001
Demographics
 Male sex 1.38 (1.27, 1.51) < .0001 1.38 (1.27, 1.51) < .0001
 Age 1.03 (1.02, 1.03) < .0001 1.03 (1.02, 1.03) < .0001
Urbanization level, %
 Level 1: urban area 1.70 (1.42, 2.03) < .0001 1.69 (1.46, 1.95) < .0001
 Level 2: metro area 1.40 (1.16, 1.69) 0.0005 1.45 (1.25, 1.69) < .0001
 Level 3: suburban area 1.09 (0.91, 1.32) 0.3524 1.10 (0.94, 1.27) 0.2392
 Level 4: countryside area Reference Reference
Insurance premium level, % (New Taiwan dollars)
 Dependent Reference Reference
 No/poverty income level ($1–$19,999) 1.06 (0.94, 1.2) 0.3171 1.06 (0.94, 1.2) 0.3171
 Middle income level ($20,000–$39,999) 1.25 (1.1, 1.44) 0.001 1.25 (1.1, 1.44) 0.001
 High income level (≥ $40,000) 0.84 (0.68, 1.04) 0.1034 0.84 (0.68, 1.04) 0.1034
Preadmission comorbidity, %
 Myocardial infarction 1.03 (0.83, 1.28) 0.7758 1.03 (0.83, 1.28) 0.7758
 Congestive heart failure 1.16 (1.04, 1.29) 0.0069 1.16 (1.04, 1.29) 0.0069
 Peripheral vascular disease 0.90 (0.74, 1.1) 0.319 0.90 (0.74, 1.10) 0.319
 Cerebrovascular disease 1.16 (1.06, 1.28) 0.0021 1.16 (1.06, 1.28) 0.0021
 Dementia 1.47 (1.31, 1.65) < .0001 1.47 (1.31, 1.65) < .0001
 Chronic pulmonary disease 1.11 (1.02, 1.21) 0.022 1.11 (1.02, 1.21) 0.022
 Rheumatologic disease 1.27 (0.91, 1.78) 0.1602 1.27 (0.91, 1.78) 0.1602
 Peptic ulcer disease 0.96 (0.88, 1.06) 0.4459 0.96 (0.88, 1.06) 0.4459
 Mild liver disease 1.07 (0.95, 1.20) 0.2567 1.07 (0.95, 1.20) 0.2567
 Diabetes without chronic complications 1.09 (0.99, 1.20) 0.0987 1.09 (0.99, 1.20) 0.0987
 Diabetes with chronic complications 0.98 (0.85, 1.13) 0.7508 0.98 (0.85, 1.13) 0.7508
 Hemiplegia or paraplegia 1.56 (0.44, 5.47) 0.4913 1.56 (0.44, 5.47) 0.4913
 Renal disease 1.15 (1.02, 1.29) 0.0184 1.15 (1.02, 1.29) 0.0184
 Any malignancy, including leukemia and lymphoma 1.40 (1.25, 1.57) < .0001 1.40 (1.25, 1.57) < .0001
 Moderate or severe liver disease 1.72 (1.40, 2.10) < .0001 1.72 (1.40, 2.10) < .0001
 Metastatic solid tumor 1.19 (0.99, 1.44) 0.0717 1.19 (0.99, 1.44) 0.0717
 AIDS/HIV 2.05 (0.66, 6.39) 0.2172 2.05 (0.66, 6.39) 0.2172
 Alcohol/drug use 1.08 (0.83, 1.42) 0.5569 1.08 (0.83, 1.42) 0.5569
 Psychiatric disorder 0.96 (0.86, 1.07) 0.4139 0.96 (0.86, 1.07) 0.4139
 Neurologic disorder 1.03 (0.90, 1.18) 0.6724 1.03 (0.90, 1.18) 0.6724
 Obesity 0.75 (0.28, 2.00) 0.567 0.75 (0.28, 2.00) 0.567
 Bed-ridden status 0.76 (0.22, 2.66) 0.6717 0.76 (0.22, 2.66) 0.6717
 Solid organ transplantation such as renal or heart transplantation 1.26 (0.4, 3.92) 0.6922 1.26 (0.40, 3.92) 0.6922
Healthcare service utilization, %
 Number of OPD visits 1.00 (1.00, 1.00) 0.9105 1.00 (1.00, 1.00) 0.9105
 Number of emergency department visits 1.02 (1.01, 1.04) 0.0002 1.02 (1.01, 1.04) 0.0002
 Number of hospital admissions 1.08 (1.06, 1.10) < .0001 1.08 (1.06, 1.10) < .0001
  1. Summary of the variables associated with 180-day mortality and 365-day mortality using the Cox regression model
  2. MI myocardial infarction, AIDS/HIV acquired immune deficiency syndrome/human immunodeficiency virus, OPD outpatient department, HR hazard ratio