Variables | Group | Baseline | 2 h | 12 h | 24 h | 48 h | 72 h | pa |
---|---|---|---|---|---|---|---|---|
PaO2/FiO2, mmHg | Failure | 222 (24) | 221 (95) | 176 (51) | 173 (43) | 145 (53) | 164 (47) | .09 |
Success | 233 (36) | 248 (69) | 249 (76) | 253 (72) | 267 (77) | 278 (77) | .00 | |
pc | .34 | .25 | .02 | .005 | .001 | .004 | .003b | |
pH | Failure | 7.42 (0.08) | 7.41 (0.09) | 7.46 (0.03) | 7.45 (0.04) | 7.45 (0.05) | 7.45 (0.09) | .71 |
Success | 7.45 (0.05) | 7.44 (0.04) | 7.44 (0.04) | 7.36 (0.79) | 7.44 (0.05) | 7.44 (0.04) | .46 | |
pc | .28 | .32 | .21 | .77 | .63 | .80 | .73 b | |
PaCO2, mmHg | Failure | 35 (6.3) | 34 (10.6) | 35 (7.0) | 41 (12.7) | 42 (16.1) | 41 (9.6) | .59 |
Success | 34 (5.7) | 35 (5.2) | 37 (10.4) | 35 (5.8) | 36 (5.0) | 37 (5.1) | .07 | |
pc | .68 | .80 | .55 | .26 | .47 | .46 | .23b | |
VT/PBW, mL/kg | Failure | 8.0 (2.4) | 7.6 (2.1) | 8.1 (2.7) | 8.2 (2.7) | 8.1 (2.0) | 9.4 (2.3) | .89 |
Success | 7.7 (1.9) | 7.9 (2.0) | 8.0 (2.0) | 7.9 (1.7) | 8.1 (1.9) | 8.2 (2.2) | .48 | |
pc | .67 | .60 | .94 | .73 | .99 | .28 | .30 b | |
RR, breaths/min | Failure | 27 (7.3) | 26 (6.5) | 23 (4.8) | 26 (6.6) | 27 (5.1) | 24 (5.9) | .89 |
Success | 25 (6.0) | 24 (4.9) | 23 (4.7) | 23 (4.5) | 22 (4.4) | 22 (4.5) | < .001 | |
pc | .49 | .22 | .79 | .12 | .03 | .35 | .84b | |
Minute ventilation, L/min | Failure | 12.7 (7.7) | 13.1 (8.3) | 14.7 (9.6) | 15.1 (10.2) | 15.0 (10.2) | 14.0 (5.0) | .99 |
Success | 10.5 (2.9) | 10.7 (3.1) | 11.1 (3.3) | 10.9 (3.1) | 10.9 (3.4) | 11.0 (3.9) | .79 | |
pc | .06 | .07 | .02 | .01 | .02 | .14 | .04b |