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Table 4 Comparisons of physiological parameters between noninvasive ventilation success and failure groups

From: A multicenter RCT of noninvasive ventilation in pneumonia-induced early mild acute respiratory distress syndrome

Variables

Group

Baseline

2 h

12 h

24 h

48 h

72 h

pa

PaO2/FiO2, mmHg

Failure

222 (24)

221 (95)

176 (51)

173 (43)

145 (53)

164 (47)

.09

Success

233 (36)

248 (69)

249 (76)

253 (72)

267 (77)

278 (77)

.00

pc

.34

.25

.02

.005

.001

.004

.003b

pH

Failure

7.42 (0.08)

7.41 (0.09)

7.46 (0.03)

7.45 (0.04)

7.45 (0.05)

7.45 (0.09)

.71

Success

7.45 (0.05)

7.44 (0.04)

7.44 (0.04)

7.36 (0.79)

7.44 (0.05)

7.44 (0.04)

.46

pc

.28

.32

.21

.77

.63

.80

.73 b

PaCO2, mmHg

Failure

35 (6.3)

34 (10.6)

35 (7.0)

41 (12.7)

42 (16.1)

41 (9.6)

.59

Success

34 (5.7)

35 (5.2)

37 (10.4)

35 (5.8)

36 (5.0)

37 (5.1)

.07

pc

.68

.80

.55

.26

.47

.46

.23b

VT/PBW, mL/kg

Failure

8.0 (2.4)

7.6 (2.1)

8.1 (2.7)

8.2 (2.7)

8.1 (2.0)

9.4 (2.3)

.89

Success

7.7 (1.9)

7.9 (2.0)

8.0 (2.0)

7.9 (1.7)

8.1 (1.9)

8.2 (2.2)

.48

pc

.67

.60

.94

.73

.99

.28

.30 b

RR, breaths/min

Failure

27 (7.3)

26 (6.5)

23 (4.8)

26 (6.6)

27 (5.1)

24 (5.9)

.89

Success

25 (6.0)

24 (4.9)

23 (4.7)

23 (4.5)

22 (4.4)

22 (4.5)

< .001

pc

.49

.22

.79

.12

.03

.35

.84b

Minute ventilation, L/min

Failure

12.7 (7.7)

13.1 (8.3)

14.7 (9.6)

15.1 (10.2)

15.0 (10.2)

14.0 (5.0)

.99

Success

10.5 (2.9)

10.7 (3.1)

11.1 (3.3)

10.9 (3.1)

10.9 (3.4)

11.0 (3.9)

.79

pc

.06

.07

.02

.01

.02

.14

.04b

  1. Results are means ± SDs
  2. NIV noninvasive ventilation, VT/PBW tidal volume/predicted body weight, RR respiratory rate, PaO2 partial pressure of arterial oxygen, FiO2 fraction of inspired oxygen
  3. ap for overall comparisons of differences in each group over time
  4. bp for overall comparisons of differences between groups over time
  5. cp for comparisons of differences between groups at each time point