Table 1 Characteristics of included patients according to variations of microvascular reactivity after RBC transfusion. SOFA was recorded at the inclusion, Sepsis-related Organ Failure Assessment. SAPS II was recorded at H24, Simplified Acute Physiology Score. MAP mean arterial pressure, CRT capillary refill time. Data are expressed as number, percentage or median, and interquartiles (IQRs)
From: Exploring the microvascular impact of red blood cell transfusion in intensive care unit patients
Patients’ characteristics | Worsening (n = 24) | Improving (n = 35) | p value |
|---|---|---|---|
Women (%) | 41 | 37 | 0.72 |
Age (years) | 66 [55; 76] | 66 [53; 82] | 0.91 |
Body mass index | 26 [22; 29] | 22 [19; 25] | 0.34 |
SOFA score | 4 [1; 5] | 3 [1; 5] | 0.69 |
SAPS II | 40 [22; 46] | 33 [24; 48] | 0.77 |
Length of stay in ICU (days) | 9 [4; 16] | 11 [4; 22] | 0.44 |
ICU mortality (%) | 8 | 11 | 0.98 |
Cause of admission in ICU (%) | |||
Neurologic | 4 | 11 | 0.63 |
Respiratory | 29 | 31 | 0.85 |
Circulatory | 21 | 15 | 0.51 |
Other | 46 | 43 | 0.82 |
Sepsis | 33 | 43 | 0.46 |
Comorbidity (%) | |||
Arterial hypertension | 17 | 35 | 0.13 |
Diabetes mellitus | 20 | 2 | 0.04 |
Vascular | 13 | 20 | 0.45 |
Cirrhosis | 4 | 0 | 0.22 |
Biological markers (blood) | |||
Hemoglobin (g/dL) | 7 [6.6; 7.3] | 6.9 [6.7; 7.3] | 0.53 |
Hematocrit (%) | 21.9 [19.8; 23.2] | 21.1 [19.9; 22.5] | 0.89 |
Leukocytes (× 109/L) | 4.6 [2.1; 7.3] | 10.3 [5.7; 19.7] | 0.001 |
Platelets (103/mm3) | 162 [40; 199] | 200 [97; 280] | 0.03 |
Creatinine (μmol/L) | 106 [60; 134] | 110 [72;295] | 0.56 |
Proteins (g/L) | 62 [55; 67] | 61 [53; 69] | 0.98 |
Glucose (mmol/L) | 6.7 [6; 7.8] | 6.9 [5.7; 8.7] | 0.96 |
Chloride (mmol/L) | 105 [98; 105] | 102 [98; 106] | 0.73 |
Total bilirubin (μmol/L) | 13 [8.2; 26.5] | 11 [6; 21] | 0.53 |
Hemodynamic parameters | |||
MAP (mmHg) | 74 [68; 84] | 77 [71; 83] | 0.88 |
Norepinephrine (%) | 4 | 11 | 0.64 |
Cardiac Index (L/min/s) | 2.8 [2.6; 2.9] | 3.6 [2.9; 4.3] | 0.07 |
Knee CRT (s) | 1.9 [1.5; 2.1] | 2.2 [1.9; 3.0] | 0.14 |
Central body temperature (°C) | 36.8 [36.3; 37.2] | 36.9 [36.7; 37.4] | 0.84 |
Skin temperature (°C) | 29.8 [29.0; 30.8] | 30 [29.5; 30.8] | 0.32 |
Packed RBC characteristic | |||
pRBC age (days) | 25 [18; 30] | 27 [18; 30] | 0.34 |